{"title":"Fisher-Kolmogorov模型的非消失锐前行波解。","authors":"Maud El-Hachem, Scott W McCue, Matthew J Simpson","doi":"10.1093/imammb/dqac004","DOIUrl":null,"url":null,"abstract":"<p><p>The Fisher-Kolmogorov-Petrovsky-Piskunov (KPP) model, and generalizations thereof, involves simple reaction-diffusion equations for biological invasion that assume individuals in the population undergo linear diffusion with diffusivity $D$, and logistic proliferation with rate $\\lambda $. For the Fisher-KPP model, biologically relevant initial conditions lead to long-time travelling wave solutions that move with speed $c=2\\sqrt {\\lambda D}$. Despite these attractive features, there are several biological limitations of travelling wave solutions of the Fisher-KPP model. First, these travelling wave solutions do not predict a well-defined invasion front. Second, biologically relevant initial conditions lead to travelling waves that move with speed $c=2\\sqrt {\\lambda D}> 0$. This means that, for biologically relevant initial data, the Fisher-KPP model cannot be used to study invasion with $c \\ne 2\\sqrt {\\lambda D}$, or retreating travelling waves with $c < 0$. Here, we reformulate the Fisher-KPP model as a moving boundary problem and show that this reformulated model alleviates the key limitations of the Fisher-KPP model. Travelling wave solutions of the moving boundary problem predict a well-defined front that can propagate with any wave speed, $-\\infty < c < \\infty $. Here, we establish these results using a combination of high-accuracy numerical simulations of the time-dependent partial differential equation, phase plane analysis and perturbation methods. All software required to replicate this work is available on GitHub.</p>","PeriodicalId":94130,"journal":{"name":"Mathematical medicine and biology : a journal of the IMA","volume":" ","pages":"226-250"},"PeriodicalIF":0.0000,"publicationDate":"2022-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Non-vanishing sharp-fronted travelling wave solutions of the Fisher-Kolmogorov model.\",\"authors\":\"Maud El-Hachem, Scott W McCue, Matthew J Simpson\",\"doi\":\"10.1093/imammb/dqac004\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The Fisher-Kolmogorov-Petrovsky-Piskunov (KPP) model, and generalizations thereof, involves simple reaction-diffusion equations for biological invasion that assume individuals in the population undergo linear diffusion with diffusivity $D$, and logistic proliferation with rate $\\\\lambda $. For the Fisher-KPP model, biologically relevant initial conditions lead to long-time travelling wave solutions that move with speed $c=2\\\\sqrt {\\\\lambda D}$. Despite these attractive features, there are several biological limitations of travelling wave solutions of the Fisher-KPP model. First, these travelling wave solutions do not predict a well-defined invasion front. Second, biologically relevant initial conditions lead to travelling waves that move with speed $c=2\\\\sqrt {\\\\lambda D}> 0$. This means that, for biologically relevant initial data, the Fisher-KPP model cannot be used to study invasion with $c \\\\ne 2\\\\sqrt {\\\\lambda D}$, or retreating travelling waves with $c < 0$. Here, we reformulate the Fisher-KPP model as a moving boundary problem and show that this reformulated model alleviates the key limitations of the Fisher-KPP model. Travelling wave solutions of the moving boundary problem predict a well-defined front that can propagate with any wave speed, $-\\\\infty < c < \\\\infty $. Here, we establish these results using a combination of high-accuracy numerical simulations of the time-dependent partial differential equation, phase plane analysis and perturbation methods. All software required to replicate this work is available on GitHub.</p>\",\"PeriodicalId\":94130,\"journal\":{\"name\":\"Mathematical medicine and biology : a journal of the IMA\",\"volume\":\" \",\"pages\":\"226-250\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-09-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Mathematical medicine and biology : a journal of the IMA\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://doi.org/10.1093/imammb/dqac004\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Mathematical medicine and biology : a journal of the IMA","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1093/imammb/dqac004","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Non-vanishing sharp-fronted travelling wave solutions of the Fisher-Kolmogorov model.
The Fisher-Kolmogorov-Petrovsky-Piskunov (KPP) model, and generalizations thereof, involves simple reaction-diffusion equations for biological invasion that assume individuals in the population undergo linear diffusion with diffusivity $D$, and logistic proliferation with rate $\lambda $. For the Fisher-KPP model, biologically relevant initial conditions lead to long-time travelling wave solutions that move with speed $c=2\sqrt {\lambda D}$. Despite these attractive features, there are several biological limitations of travelling wave solutions of the Fisher-KPP model. First, these travelling wave solutions do not predict a well-defined invasion front. Second, biologically relevant initial conditions lead to travelling waves that move with speed $c=2\sqrt {\lambda D}> 0$. This means that, for biologically relevant initial data, the Fisher-KPP model cannot be used to study invasion with $c \ne 2\sqrt {\lambda D}$, or retreating travelling waves with $c < 0$. Here, we reformulate the Fisher-KPP model as a moving boundary problem and show that this reformulated model alleviates the key limitations of the Fisher-KPP model. Travelling wave solutions of the moving boundary problem predict a well-defined front that can propagate with any wave speed, $-\infty < c < \infty $. Here, we establish these results using a combination of high-accuracy numerical simulations of the time-dependent partial differential equation, phase plane analysis and perturbation methods. All software required to replicate this work is available on GitHub.