皮克林乳剂综述:展望与应用。

Fernanda Brito de Carvalho-Guimarães, Kamila Leal Correa, Tatiane Pereira de Souza, Jesus Rafael Rodríguez Amado, Roseane Maria Ribeiro-Costa, José Otávio Carréra Silva-Júnior
{"title":"皮克林乳剂综述:展望与应用。","authors":"Fernanda Brito de Carvalho-Guimarães,&nbsp;Kamila Leal Correa,&nbsp;Tatiane Pereira de Souza,&nbsp;Jesus Rafael Rodríguez Amado,&nbsp;Roseane Maria Ribeiro-Costa,&nbsp;José Otávio Carréra Silva-Júnior","doi":"10.3390/ph15111413","DOIUrl":null,"url":null,"abstract":"<p><p>Pickering emulsions are systems composed of two immiscible fluids stabilized by organic or inorganic solid particles. These solid particles of certain dimensions (micro- or nano-particles), and desired wettability, have been shown to be an alternative to conventional emulsifiers. The use of biodegradable and biocompatible stabilizers of natural origin, such as clay minerals, presents a promising future for the development of Pickering emulsions and, with this, they deliver some advantages, especially in the area of biomedicine. In this review, the effects and characteristics of microparticles in the preparation and properties of Pickering emulsions are presented. The objective of this review is to provide a theoretical basis for a broader type of emulsion, in addition to reviewing the main aspects related to the mechanisms and applications to promote its stability. Through this review, we highlight the use of this type of emulsion and its excellent properties as permeability promoters of solid particles, providing ideal results for local drug delivery and use in Pickering emulsions.</p>","PeriodicalId":520747,"journal":{"name":"Pharmaceuticals (Basel, Switzerland)","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698490/pdf/","citationCount":"10","resultStr":"{\"title\":\"A Review of Pickering Emulsions: Perspectives and Applications.\",\"authors\":\"Fernanda Brito de Carvalho-Guimarães,&nbsp;Kamila Leal Correa,&nbsp;Tatiane Pereira de Souza,&nbsp;Jesus Rafael Rodríguez Amado,&nbsp;Roseane Maria Ribeiro-Costa,&nbsp;José Otávio Carréra Silva-Júnior\",\"doi\":\"10.3390/ph15111413\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Pickering emulsions are systems composed of two immiscible fluids stabilized by organic or inorganic solid particles. These solid particles of certain dimensions (micro- or nano-particles), and desired wettability, have been shown to be an alternative to conventional emulsifiers. The use of biodegradable and biocompatible stabilizers of natural origin, such as clay minerals, presents a promising future for the development of Pickering emulsions and, with this, they deliver some advantages, especially in the area of biomedicine. In this review, the effects and characteristics of microparticles in the preparation and properties of Pickering emulsions are presented. The objective of this review is to provide a theoretical basis for a broader type of emulsion, in addition to reviewing the main aspects related to the mechanisms and applications to promote its stability. Through this review, we highlight the use of this type of emulsion and its excellent properties as permeability promoters of solid particles, providing ideal results for local drug delivery and use in Pickering emulsions.</p>\",\"PeriodicalId\":520747,\"journal\":{\"name\":\"Pharmaceuticals (Basel, Switzerland)\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-11-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698490/pdf/\",\"citationCount\":\"10\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Pharmaceuticals (Basel, Switzerland)\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.3390/ph15111413\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pharmaceuticals (Basel, Switzerland)","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3390/ph15111413","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 10

摘要

皮克林乳剂是由有机或无机固体颗粒稳定的两种不混溶流体组成的系统。这些具有一定尺寸的固体颗粒(微或纳米颗粒)和理想的润湿性,已被证明是传统乳化剂的替代品。使用天然来源的可生物降解和生物相容性稳定剂,如粘土矿物,为皮克林乳剂的发展提供了一个有希望的未来,并因此提供了一些优势,特别是在生物医学领域。本文综述了微颗粒在皮克林乳剂制备中的作用、特点及其性能。本文综述了促进乳液稳定性的机理和应用的主要方面,旨在为更广泛类型的乳液提供理论依据。通过本文的综述,我们重点介绍了这类乳剂的用途及其作为固体颗粒渗透性促进剂的优异性能,为皮克林乳剂的局部药物传递和使用提供了理想的结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

A Review of Pickering Emulsions: Perspectives and Applications.

A Review of Pickering Emulsions: Perspectives and Applications.

A Review of Pickering Emulsions: Perspectives and Applications.

A Review of Pickering Emulsions: Perspectives and Applications.

Pickering emulsions are systems composed of two immiscible fluids stabilized by organic or inorganic solid particles. These solid particles of certain dimensions (micro- or nano-particles), and desired wettability, have been shown to be an alternative to conventional emulsifiers. The use of biodegradable and biocompatible stabilizers of natural origin, such as clay minerals, presents a promising future for the development of Pickering emulsions and, with this, they deliver some advantages, especially in the area of biomedicine. In this review, the effects and characteristics of microparticles in the preparation and properties of Pickering emulsions are presented. The objective of this review is to provide a theoretical basis for a broader type of emulsion, in addition to reviewing the main aspects related to the mechanisms and applications to promote its stability. Through this review, we highlight the use of this type of emulsion and its excellent properties as permeability promoters of solid particles, providing ideal results for local drug delivery and use in Pickering emulsions.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信