基于多阶段时间卷积网络的COVID-19变异分类。

Waseem Ullah, Amin Ullah, Khalid Mahmood Malik, Abdul Khader Jilani Saudagar, Muhammad Badruddin Khan, Mozaherul Hoque Abul Hasanat, Abdullah AlTameem, Mohammed AlKhathami
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引用次数: 2

摘要

新型冠状病毒病COVID-19 (SARS-CoV-2)的爆发已发展成为全球性流行病。由于致病性病毒传播率高,需要准确识别和早期预测,以便后续治疗。此外,病毒的多态特性使其能够进化和适应各种环境,这使得预测变得困难。然而,其他疾病,如登革热、MERS-CoV、埃博拉、SARS-CoV-1和流感,需要使用基于其基因组信息的预测器。为了缓解这种情况,我们提出了一种基于深度学习的机制来分类各种SARS-CoV-2病毒变体,包括最近的Omicron。我们的模型使用神经网络和时间卷积神经网络来准确识别COVID-19的不同变体。该模型首先在数字描述符中对序列进行编码,然后利用卷积运算对编码序列进行判别特征提取。使用时间卷积网络收集特征之间的顺序关系,以准确分类COVID-19变体。我们从NCBI收集了最近的数据,在这些数据上,所提出的方法以高利润率优于各种基线。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Multi-Stage Temporal Convolution Network for COVID-19 Variant Classification.

Multi-Stage Temporal Convolution Network for COVID-19 Variant Classification.

Multi-Stage Temporal Convolution Network for COVID-19 Variant Classification.

Multi-Stage Temporal Convolution Network for COVID-19 Variant Classification.

The outbreak of the novel coronavirus disease COVID-19 (SARS-CoV-2) has developed into a global epidemic. Due to the pathogenic virus's high transmission rate, accurate identification and early prediction are required for subsequent therapy. Moreover, the virus's polymorphic nature allows it to evolve and adapt to various environments, making prediction difficult. However, other diseases, such as dengue, MERS-CoV, Ebola, SARS-CoV-1, and influenza, necessitate the employment of a predictor based on their genomic information. To alleviate the situation, we propose a deep learning-based mechanism for the classification of various SARS-CoV-2 virus variants, including the most recent, Omicron. Our model uses a neural network with a temporal convolution neural network to accurately identify different variants of COVID-19. The proposed model first encodes the sequences in the numerical descriptor, and then the convolution operation is applied for discriminative feature extraction from the encoded sequences. The sequential relations between the features are collected using a temporal convolution network to classify COVID-19 variants accurately. We collected recent data from the NCBI, on which the proposed method outperforms various baselines with a high margin.

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