2022年6月至9月，在以色列接种疫苗的个体中，BA.1和BA.5突破感染后，Omicron BA.2.75变体被有效中和。

IF 7.8

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin Pub Date : 2022-11-01 DOI:10.2807/1560-7917.ES.2022.27.44.2200785

Nofar Atari, Limor Kliker, Neta Zuckerman, Bayan Abd Elkader, Yael Weiss-Ottolenghi, Ella Mendelson, Yitshak Kreiss, Gili Regev-Yochay, Michal Mandelboim

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引用次数: 2

摘要

我们评估了以色列完全接种(三剂Comirnaty疫苗)的卫生保健工作者(HCW)中针对野生型(WT) SARS-CoV-2和四种Omicron变体(BA.1、BA.2、BA.5和BA.2.75)的中和抗体滴度，这些卫生保健工作者(HCW)感染了突破性的BA.1/BA5。与未接种疫苗的HCW相比，接种个体的Omicron突破感染导致针对WT和Omicron变体的中和抗体增加。从ba1或ba5感染中恢复的HCW对ba2.75表现出相似的中和抗体水平。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Omicron BA.2.75 variant is efficiently neutralised following BA.1 and BA.5 breakthrough infection in vaccinated individuals, Israel, June to September 2022.

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Omicron BA.2.75 variant is efficiently neutralised following BA.1 and BA.5 breakthrough infection in vaccinated individuals, Israel, June to September 2022.

We evaluated neutralising antibody titres against wild type (WT) SARS-CoV-2 and four Omicron variants (BA.1, BA.2, BA.5 and BA.2.75) in fully vaccinated (three doses of Comirnaty vaccine) healthcare workers (HCW) in Israel who had breakthrough BA.1/BA5 infections. Omicron breakthrough infections in vaccinated individuals resulted in increased neutralising antibodies against the WT and Omicron variants compared with vaccinated uninfected HCW. HCW who recovered from BA.1 or BA.5 infections showed similar neutralising antibodies levels against BA.2.75.

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来源期刊

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

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