伊朗SARS-CoV-2全序列变异分析

IF 2.1 4区 医学 Q3 VIROLOGY
Future Virology Pub Date : 2022-10-01 Epub Date: 2022-10-22 DOI:10.2217/fvl-2021-0056
Jale Moradi, Parnia Moradi, Amir H Alvandi, Ramin Abiri, Mohsen Moghoofei
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引用次数: 1

摘要

目的:SARS-CoV-2是一种在中国发现并迅速传播到世界各地的新型冠状病毒。作者研究了伊朗SARS-CoV-2基因组中的核苷酸和氨基酸变异,以及病毒基因组中的系统发育和进化事件。材料和方法:纳入大流行开始至2021年10月15日期间公开发布的所有SARS-CoV-2序列。结果:突变主要发生在疫苗靶蛋白、刺突蛋白和核衣壳蛋白以及非结构蛋白。在大流行的早期阶段传播的大多数病毒属于B.4谱系。结论:我们发现了病毒种群在伊朗的流行。因此,追踪病毒在伊朗的变异,并将其与附近社区的各种变异进行比较,可能会揭示未来变异引入的模式。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Variation analysis of SARS-CoV-2 complete sequences from Iran.

Variation analysis of SARS-CoV-2 complete sequences from Iran.

Variation analysis of SARS-CoV-2 complete sequences from Iran.

Variation analysis of SARS-CoV-2 complete sequences from Iran.

Aim: SARS-CoV-2 is an emerging coronavirus that was discovered in China and rapidly spread throughout the world. The authors looked at nucleotide and amino acid variations in SARS-CoV-2 genomes, as well as phylogenetic and evolutionary events in viral genomes, in Iran. Materials & methods: All SARS-CoV-2 sequences that were publicly released between the start of the pandemic and 15 October 2021 were included. Results: The majority of mutations were found in vaccine target proteins, Spike and Nucleocapsid proteins, and nonstructural proteins. The majority of the viruses that circulated in the early stages of the pandemic belonged to the B.4 lineage. Conclusion: We discovered the prevalence of viral populations in Iran. As a result, tracking the virus's variation in Iran and comparing it with a variety of nearby neighborhoods may reveal a pattern for future variant introductions.

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来源期刊
Future Virology
Future Virology 医学-病毒学
CiteScore
4.00
自引率
3.20%
发文量
84
审稿时长
6-12 weeks
期刊介绍: Future Virology is a peer-reviewed journal that delivers essential information in concise, at-a-glance article formats. Key advances in the field are reported and analyzed by international experts, providing an authoritative but accessible forum for this ever-expanding area of research. It is an interdisciplinary forum for all scientists working in the field today.
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