对接受卵巢子宫切除术的狗来说,术后针灸与术前针灸或美洛昔康一样有效:一项盲随机研究。

IF 0.9 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE
Ana Carla Zago Basilio Ferro, Caroline Cannolas, Juliana Cristianini Reginato, Stelio Pacca Loureiro Luna
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引用次数: 1

摘要

背景:针灸具有与非甾体抗炎药和阿片类药物相同的镇痛作用。在难以控制的动物身上进行术前针灸是一项挑战,而术后残余的麻醉效果有助于术后针灸的进行。目的:比较术前针刺或美洛昔康与术后针刺对卵巢子宫切除术后镇痛的影响。方法:这是一项水平前瞻性阳性对照盲随机实验研究。36只狗被随机分为三组:GA(预先针刺)、GPA(术后针刺)和GM(美洛昔康0.2mg/kg,术前静脉注射)。用乙酰丙嗪(0.05mg/kg IM)镇静后,用丙泊酚(5.3±0.3mg/kg)诱导麻醉,并用异氟醚/O2维持麻醉。芬太尼(2μg/kg,IV)在手术前立即给药。在手术前(GA)或手术后立即(GPA),在大肠4、脾6和胃36穴位进行双侧针刺20分钟。在卵巢子宫切除术前和术后24小时,由一名对治疗视而不见的观察者使用格拉斯哥量表评估疼痛。评分≥6的狗接受吗啡(0.5 mg/kg IM)的抢救性镇痛。非参数数据采用Kruskal-Wallis检验,然后采用Dunn检验,参数数据采用ANOVA,然后采用Tukey检验。结果:2只GA犬和1只GPA犬接受了一次抢救性镇痛。两只转基因狗接受了抢救性镇痛,其中一只再次接受了两次治疗。两组接受抢救性镇痛的狗的数量没有差异(p=0.80)。结论:对接受卵巢子宫切除术的母狗,术后针刺与术前针刺或美洛昔康一样有效。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Postoperative Acupuncture is as Effective as Preoperative Acupuncture or Meloxicam in Dogs Undergoing Ovariohysterectomy: a Blind Randomized Study.

Background: Acupuncture has the same analgesic effect as non-steroidal antiinflammatory drugs and opioids. It is challenging to perform preoperative acupuncture in unmanageable animals, while the residual postoperative anesthetic effect facilitates the performance of acupuncture postoperatively.

Objectives: To compare preoperative acupuncture or meloxicam versus postoperative acupuncture for postoperative analgesia after ovariohysterectomy.

Methods: This is a horizontal prospective positive control blind randomized experimental study. Thirty-six dogs were randomly divided into three groups: GA (preemptive acupuncture), GPA (postoperative acupuncture), and GM (meloxicam 0.2 mg/kg IV preoperatively). After sedation with acepromazine (0.05 mg/kg IM), anesthesia was induced with propofol (5.3 ± 0.3 mg/kg) and maintained with isoflurane/O2. Fentanyl (2 μg/kg, IV) was administered immediately before surgery. Bilateral acupuncture was performed at acupoints Large intestine 4, Spleen 6, and Stomach 36 for 20 minutes, before (GA) or immediately after surgery (GPA). Pain was evaluated by an observer blind to the treatment using the Glasgow scale before and for 24 hours after ovariohysterectomy. Dogs with a score ≥ 6 received rescue analgesia with morphine (0.5 mg/kg IM). Nonparametric data were analyzed by the Kruskal-Wallis test, followed by Dunn's test and parametric data by ANOVA followed by Tukey's test.

Results: Two GA and one GPA dogs received rescue analgesia once. Two GM dogs received rescue analgesia and one of those was treated again twice. There were no differences in the number of dogs receiving rescue analgesia between groups (p = 0.80).

Conclusion: Postoperative acupuncture was as effective as preoperative acupuncture or meloxicam in female dogs undergoing ovariohysterectomy.

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来源期刊
Journal of Acupuncture and Meridian Studies
Journal of Acupuncture and Meridian Studies INTEGRATIVE & COMPLEMENTARY MEDICINE-
CiteScore
1.50
自引率
10.00%
发文量
35
审稿时长
12 weeks
期刊介绍: The Journal of Acupuncture and Meridian Studies is a quarterly, peer-reviewed journal featuring high-quality studies related to basic and clinical acupuncture and meridian research. It also includes new paradigm of integrative research, covering East–West and traditional–modern medicine. Manuscripts should fall into one of the categories: topical review, original research paper, brief ... click here for full Aims & Scope The Journal of Acupuncture and Meridian Studies is a quarterly, peer-reviewed journal featuring high-quality studies related to basic and clinical acupuncture and meridian research. It also includes new paradigm of integrative research, covering East–West and traditional–modern medicine.
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