用于DOAC逆转的新药物:一项实用的管理综述。

The British journal of cardiology Pub Date : 2022-01-12 eCollection Date: 2022-01-01 DOI:10.5837/bjc.2022.001
Katie White, Uzma Faruqi, Alexander Ander T Cohen
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引用次数: 9

摘要

出血是与抗凝剂相关的最常见和最令人担忧的不良事件。根据出血的严重程度,可采用各种方法处理出血,对于严重或危及生命的出血,应指出并建议使用特定的解毒剂。这篇综述提供了关于特定的直接口服抗凝剂(DOAC)逆转剂,即解毒剂的指导。我们讨论了它们的使用适应症、剂量和潜在的副作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
New agents for DOAC reversal: a practical management review.

Bleeding is the commonest and most concerning adverse event associated with anticoagulants. Bleeding, depending on the severity, is managed in various ways, and for severe or life-threatening bleeding, specific antidotes are indicated and recommended. This review provides guidance relating to specific direct oral anticoagulant (DOAC) reversal agents, the antidotes. We discuss their indications for use, dosing, and potential side effects.

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