Francesca Amoroso, Alexandra Miere, Khaled El Matri, Salomon Yves Cohen, Camille Jung, Carlotta Pallone, Elsa Bruyere, Leila El Matri, Eric H Souied
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引用次数: 0
摘要
目的:分析病理性近视眼继发性黄斑新生血管渗出活性与病灶性脉络膜厚度增加的关系。方法:回顾性分析包括病理性近视的眼睛，表现为活动性MNV下局部ChT升高。所有患者均接受治疗，并由两名经验丰富的眼科医生在每次玻璃体内注射前后测量ChT。结果:52例近视MNV患者共52只眼(男19例，女33例)纳入分析。T-1时的ChT平均为51.09±33.56 μ m，而在MNV激活(T0)时，ChT明显变厚，为85.11±43.99 μ m (P < 0.001)。单次玻璃体内注射后，ChT显著降低至53.23±34.15 μ m (P < 0.001)。结论:本研究表明，局灶性ChT变化可能被认为是高度近视患者MNV的一个有趣的必然征象，表明近视新生血管的活动。
FOCAL CHOROIDAL THICKNESS HEMODYNAMICS AS a SIGN OF MACULAR NEOVASCULARIZATION ACTIVITY IN PATHOLOGIC MYOPIA.
Purpose: To analyze the relationship between a focal increase of choroidal thickness (ChT) and exudative activity of macular neovascularization (MNV) secondary to pathologic myopia.
Methods: Retrospective analysis including eyes with pathologic myopia presenting with a focally increased ChT underneath active MNV. All patients included were treated, and ChT was measured before and after each intravitreal injection by two experienced ophthalmologists.
Results: Fifty-two eyes of 52 patients with myopic MNV (19 men and 33 women) were included in this analysis. ChT at T-1 averaged 51.09 ± 33.56 μ m, whereas at the time of MNV activation (T0), ChT was significantly thicker: 85.11 ± 43.99 μ m ( P < 0.001). After a single intravitreal injection, the ChT significantly decreased to 53.23 ± 34.15 μ m ( P < 0.001).
Conclusion: This study showed that focal ChT variations may be considered an interesting corollary sign of MNV in high myopic patients, indicating the activity of myopic neovascularization.
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