纳米材料在胃肠道肿瘤中的应用综述

Frontiers in Medical Technology Pub Date : 2022-09-01 eCollection Date: 2022-01-01 DOI:10.3389/fmedt.2022.997123
Rahul Kanaoujiya, Dipiti Porwal, Shekhar Srivastava
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引用次数: 4

摘要

纳米技术是诊断和治疗各种疾病的新兴和先进的研究领域。随着纳米技术的发展,不同的纳米颗粒因其独特的光学特性、优异的生物相容性、表面效应和小尺寸效应而被用于癌症的治疗。纳米粒子是具有1到100纳米的特定尺寸的粒子。这些纳米颗粒有零维、一维、二维和三维等。目前,基于纳米颗粒的形态、组成、与靶细胞的相互作用,各种各样的研究都集中在为医学应用而定制的纳米颗粒的合成上,这些纳米颗粒可用于癌症治疗。胃肠道肿瘤是最致命的癌症类型之一,复发率最高。由于胃肠道肿瘤位置深、手术复杂,其诊断和治疗极具挑战性。纳米技术为胃肠道疾病提供了快速诊断和即时治疗。各种纳米材料被用于胃肠道疾病的诊断和治疗。纳米颗粒作为诊断和治疗工具直接靶向肿瘤细胞,促进肿瘤细胞的识别和清除。许多纳米粒子被开发用于量子点(QDs),碳纳米管(CNTs),金属纳米粒子(MNPs),树状聚合物等。本文综述了在胃肠道疾病的诊断和治疗中最有前途的纳米材料。这篇综述试图整合最新的纳米材料的众多用途,它们在治疗胃肠道疾病方面具有巨大的潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Applications of nanomaterials for gastrointestinal tumors: A review.

Applications of nanomaterials for gastrointestinal tumors: A review.

Applications of nanomaterials for gastrointestinal tumors: A review.

Nanotechnology is the emerging and advance field of research for the diagnosis and treatment of various diseases. With the development of nanotechnology, different nanoparticles are used in the treatment of cancer due to their unique optical properties, excellent biocompatibility, surface effects, and small size effects. Nanoparticles are the particles which have the particular size from 1 to 100 nm. These nanoparticles are zero dimension, one dimension, two dimension and three dimension etc. In present scenario a variety of research is focused on the tailored synthesis of nanoparticles for medicinal applications that can be used for cancer treatment based on the morphology, composition, interaction with target cell. The gastrointestinal (GI) tumors are found one of the deadest cancer types with highest reoccurrence rates. The diagnosis and treatment of gastrointestinal cancer is very challenging due to its deep location and complicated surgery. Nanotechnology provides fast diagnosis and immediate treatment for the gastrointestinal disease. A variety of nanomaterials are used for the diagnosis and treatment of GI disease. Nanoparticles target directly to the tumor cell as diagnostic and therapeutic tools facilitating the identification and removal of tumor cells. A number of nanoparticles are developed for the uses are quantum dots (QDs), carbon nanotubes (CNTs), metallic nanoparticles (MNPs), Dendrimers etc. This review article gives an overview of the most promising nanomaterials used for the diagnosis and treatment of GI diseases. This review attempts to incorporate numerous uses for the most current nanomaterials, which have great potential for treating gastrointestinal diseases.

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