Bruna Teixeira da Costa, Glauber Rocha Lima Araújo, Ronaldo Teixeira da Silva Júnior, Luana Kauany de Sá Santos, Vinícius Lima de Souza Gonçalves, Daniel Bastos Alves Lima, Beatriz Rocha Cuzzuol, Jonathan Santos Apolonio, Lorena Sousa de Carvalho, Hanna Santos Marques, Camilo Santana Silva, Isadora de Souza Barcelos, Márcio Vasconcelos Oliveira, Fabrício Freire de Melo
{"title":"营养物质对重症COVID-19患者免疫调节的影响:目前的知识","authors":"Bruna Teixeira da Costa, Glauber Rocha Lima Araújo, Ronaldo Teixeira da Silva Júnior, Luana Kauany de Sá Santos, Vinícius Lima de Souza Gonçalves, Daniel Bastos Alves Lima, Beatriz Rocha Cuzzuol, Jonathan Santos Apolonio, Lorena Sousa de Carvalho, Hanna Santos Marques, Camilo Santana Silva, Isadora de Souza Barcelos, Márcio Vasconcelos Oliveira, Fabrício Freire de Melo","doi":"10.5492/wjccm.v11.i4.201","DOIUrl":null,"url":null,"abstract":"<p><p>Recent research has demonstrated that critically ill patients with coronavirus disease 2019 (COVID-19) show significant immune system dysregulation. Due to that, some nutrients that influence immunomodulation have been suggested as a form of treatment against the infection. This review collected the information on the impact of vitamins on the prognosis of COVID-19, with the intention of facilitating treatment and prevention of the disease risk status in patients. The collected information was obtained using the PubMed electronic database by searching for articles that relate COVID-19 and the mechanisms/effects of the nutrients: Proteins, glucose, lipids, vitamin B12, vitamin D, calcium, iron, copper, zinc, and magnesium, including prospective, retrospective, and support articles. The findings reveal an optimal response related mainly to omega-3, eicosapentaenoic acid, docosahexaenoic acid, calcium, and iron that might represent benefits in the treatment of critically ill patients. However, nutrient supplementation should be done with caution due to the limited availability of randomized controlled studies.</p>","PeriodicalId":66959,"journal":{"name":"世界危重病急救学杂志(英文版)","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2022-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/89/98/WJCCM-11-201.PMC9305681.pdf","citationCount":"1","resultStr":"{\"title\":\"Effects of nutrients on immunomodulation in patients with severe COVID-19: Current knowledge.\",\"authors\":\"Bruna Teixeira da Costa, Glauber Rocha Lima Araújo, Ronaldo Teixeira da Silva Júnior, Luana Kauany de Sá Santos, Vinícius Lima de Souza Gonçalves, Daniel Bastos Alves Lima, Beatriz Rocha Cuzzuol, Jonathan Santos Apolonio, Lorena Sousa de Carvalho, Hanna Santos Marques, Camilo Santana Silva, Isadora de Souza Barcelos, Márcio Vasconcelos Oliveira, Fabrício Freire de Melo\",\"doi\":\"10.5492/wjccm.v11.i4.201\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Recent research has demonstrated that critically ill patients with coronavirus disease 2019 (COVID-19) show significant immune system dysregulation. Due to that, some nutrients that influence immunomodulation have been suggested as a form of treatment against the infection. This review collected the information on the impact of vitamins on the prognosis of COVID-19, with the intention of facilitating treatment and prevention of the disease risk status in patients. The collected information was obtained using the PubMed electronic database by searching for articles that relate COVID-19 and the mechanisms/effects of the nutrients: Proteins, glucose, lipids, vitamin B12, vitamin D, calcium, iron, copper, zinc, and magnesium, including prospective, retrospective, and support articles. The findings reveal an optimal response related mainly to omega-3, eicosapentaenoic acid, docosahexaenoic acid, calcium, and iron that might represent benefits in the treatment of critically ill patients. However, nutrient supplementation should be done with caution due to the limited availability of randomized controlled studies.</p>\",\"PeriodicalId\":66959,\"journal\":{\"name\":\"世界危重病急救学杂志(英文版)\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-07-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/89/98/WJCCM-11-201.PMC9305681.pdf\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"世界危重病急救学杂志(英文版)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5492/wjccm.v11.i4.201\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"世界危重病急救学杂志(英文版)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5492/wjccm.v11.i4.201","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Effects of nutrients on immunomodulation in patients with severe COVID-19: Current knowledge.
Recent research has demonstrated that critically ill patients with coronavirus disease 2019 (COVID-19) show significant immune system dysregulation. Due to that, some nutrients that influence immunomodulation have been suggested as a form of treatment against the infection. This review collected the information on the impact of vitamins on the prognosis of COVID-19, with the intention of facilitating treatment and prevention of the disease risk status in patients. The collected information was obtained using the PubMed electronic database by searching for articles that relate COVID-19 and the mechanisms/effects of the nutrients: Proteins, glucose, lipids, vitamin B12, vitamin D, calcium, iron, copper, zinc, and magnesium, including prospective, retrospective, and support articles. The findings reveal an optimal response related mainly to omega-3, eicosapentaenoic acid, docosahexaenoic acid, calcium, and iron that might represent benefits in the treatment of critically ill patients. However, nutrient supplementation should be done with caution due to the limited availability of randomized controlled studies.
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