短肠的双胞移植:文献回顾和一个复杂病例的讨论。

Q3 Medicine
Sara Ugolini, Riccardo Coletta, Antonino Morabito
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引用次数: 0

摘要

儿科肠道移植(IT)由于解剖比例失调,在等待名单上死亡率最高。活体供体IT (LDIT)提供了最好的优势,当在同卵同卵双胞胎中进行时,它也受益于独特的免疫学。据MEDLINE/Pubmed报道,已在7例(男性6:7,中位年龄32岁)中进行了双胞LDIT。所有患者术后均未接受免疫抑制。只有一例小儿双胎LDIT采用160厘米的回肠中束:需要插入4/5厘米的动脉移植物,以确保与肾下腹主动脉前壁无张力吻合。静脉吻合术直接与下腔静脉吻合。我们提出了一个13个月大的SBS患者的案例,其中双胞胎ldit与父母进行了讨论,他们在仔细分析和伦理考虑后决定等待。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Intestinal twin-to-twin transplant for short gut: Review of the literature and discussion of a complex case.

Paediatric Intestinal Transplantation (IT) presents the highest mortality on the waiting-list due to anatomical disproportion. Living-Donor IT (LDIT) offers the best advantages and when performed among identical monozygotic twins, it also benefits from unique immunology. According to MEDLINE/Pubmed, twin-to-twin LDIT has been performed in seven cases (6:7 males, median age of 32 years). None of the patients received immunosuppression postoperatively. Only one paediatric twinto- twin LDIT was carried out with a 160-cm mid-ileum tract: an interposed 4/5-cm arterial graft was required to ensure a tensionfree anastomosis to the anterior wall of the infra-renal abdominal aorta. In contrast, venous anastomosis was done directly to the inferior cava vein. We present a case for debate of a 13- month-old SBS patient where a twin-LDIT was discussed with parents, who decided to wait after careful analysis and ethical considerations.

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来源期刊
Pediatria Medica e Chirurgica
Pediatria Medica e Chirurgica Medicine-Pediatrics, Perinatology and Child Health
CiteScore
0.70
自引率
0.00%
发文量
21
审稿时长
10 weeks
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