急性冠状动脉综合征患者的生活质量和抑郁评估:一项横断面研究

Q2 Medicine
Treesa P Varghese, P R Anand Vijaya Kumar
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引用次数: 0

摘要

目的:急性冠状动脉综合征(ACS)是目前工业化国家的主要死因。急性冠状动脉综合征后的发病率包括影响患者整个生活状况和生活质量(QoL)的身体和精神障碍。本研究的主要目的是评估 ACS 患者的 QoL 和抑郁情况:这是一项横断面观察研究。本研究共纳入了 112 名符合纳入标准的患者。研究人员向患者发放了一份半结构式问卷,以收集患者的数据。研究对象包括年龄在 18-80 岁之间的男性和女性急性心肌梗死患者;被诊断为非 ST 段抬高型心肌梗死(NSTEMI)或 STEMI 或心绞痛的患者。患有严重身心疾病和痴呆症的患者不在研究范围内。QoL 和抑郁评估分别采用兰德 36 项健康调查和汉密尔顿抑郁量表进行:在112名ACS后患者中,78人为男性,38人为女性。研究对象的平均年龄为(64.25 ± 9.029)岁,大多数人的年龄在 61-70 岁之间。大多数研究对象已婚(71.5%),与家人同住(92.9%)。在该研究群体中,42.9%的人至少接受过高中教育(SSLC),54.5%的人是全职雇员。大多数患者(91.1%)定期服药,55.4%的患者表示定期接受随访。本研究发现,在各种因素中,年龄较大、女性、收入较低、失业、教育程度低、服药依从性差和抑郁症状导致了患者的 QoL 较差:本研究证实抑郁症状与 QoL 之间存在负相关。研究结果揭示了基层医疗诊所中普遍存在的抑郁症的严重程度,这些抑郁症没有得到诊断和治疗。因此,建议对 ACS 患者进行适当的抑郁症状筛查。因此,同时控制抑郁症和 ACS 可以获得更好的 QoL。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Quality of Life and Depression Assessment in Patients with Acute Coronary Syndrome: A Cross-Sectional Study.

Purpose: Acute Coronary Syndrome (ACS) is currently the leading cause of death in industrialized countries. Morbidity after ACS includes physical and mental disorders affecting the patient's whole life situation and Quality of Life (QoL). The main aim of the study was to assess QoL and depression among post-ACS patients.

Methods: This was a cross-sectional observational study. A total of 112 patients who fulfilled the inclusion criteria were included in this study. A semi-structured questionnaire was administered to the patients to collect data from the patients. In this study, men and women aged 18 - 80 with ACS; patients diagnosed with Non-ST Segment Elevated Myocardial Infarction (NSTEMI) or STEMI or Angina Pectoris were included. Patients with severe mental, and physical illness and dementia were excluded from the study. QoL and depression assessment was done by RAND 36-Item Health Survey and Hamilton Depression Rating scale, respectively.

Results: Among 112 post-ACS patients, 78 patients were males, and 38 patients were females. The mean age of the study population was 64.25 ± 9.029 and with most individuals in the category of 61 -70 years. The majority of study populations were married (71.5%) and lived with their families (92.9%). In this study group, 42.9 % of the population reported at least high school education (SSLC) and 54.5% were full-time employees. Most of the patients (91.1%) were taking the medication regularly, while 55.4% of patients reported regular compliance with the follow-up. This study identified that, among various factors, older age, female gender, lower income, unemployment, low education status, poor compliance with medication, and depressive symptoms led to poor QoL.

Conclusion: This study confirms a negative correlation between depressive symptoms and QoL. This study's results reveal the magnitude of depression that is prevalent in the primary health care clinic that goes undiagnosed and unmanaged. Hence, it is recommended to properly screen depressive symptoms in ACS patients. Therefore, concurrently, better QoL can be achieved by managing both depression and ACS.

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来源期刊
Cardiovascular and Hematological Disorders - Drug Targets
Cardiovascular and Hematological Disorders - Drug Targets Medicine-Cardiology and Cardiovascular Medicine
CiteScore
1.90
自引率
0.00%
发文量
36
期刊介绍: Cardiovascular & Hematological Disorders - Drug Targets aims to cover all the latest and outstanding developments on the medicinal chemistry, pharmacology, molecular biology, genomics and biochemistry of contemporary molecular targets involved in cardiovascular and hematological disorders e.g. disease specific proteins, receptors, enzymes, genes. Each issue of the journal contains a series of timely in-depth reviews written by leaders in the field covering a range of current topics on drug targets involved in cardiovascular and hematological disorders. As the discovery, identification, characterization and validation of novel human drug targets for cardiovascular and hematological drug discovery continues to grow.
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