美国未破裂胸腹主动脉瘤治疗的种族差异。

The Journal of surgical research Pub Date : 2013-09-01 Epub Date: 2013-03-27 DOI:10.1016/j.jss.2013.03.018
Dean J Arnaoutakis, Brandon W Propper, James H Black, Eric B Schneider, Ying Wei Lum, Julie A Freischlag, Bruce A Perler, Christopher J Abularrage
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引用次数: 25

摘要

目的:先前的研究发现,接受腹主动脉瘤修复术的少数患者死亡率增加。本研究的目的是确定胸腹主动脉瘤修复患者的种族差异。材料和方法:我们使用《国际疾病分类第九版临床修改代码》对2005-2009年全国住院患者样本进行了未破裂胸腹动脉瘤修复的查询。主要结果是死亡。次要结局包括术后并发症。我们进行了多变量分析,调整了年龄、性别、种族、合并症(Charlson指数)、保险类型、外科医生和医院的手术量和特征。结果:总体而言,1541名白人、207名黑人和117名西班牙裔患者接受了胸腹主动脉瘤修复。白人患者年龄偏大(P = 0.003),黑人患者糖尿病发病率较高(P = 0.04)。黑人和西班牙裔患者选择住院的可能性较小(P < 0.001),更有可能在年平均手术量较低的医院进行修复(P = 0.04)。两组术后并发症相似(P = 0.31)。在多变量分析中,死亡率增加与西班牙裔独立相关(相对比[RR], 2.57;95%置信区间[CI], 1.25-5.25;P = 0.01)、脑血管疾病(RR, 1.88;95% ci, 1.10-3.23;P = 0.02)、年龄(RR, 1.04;95% ci, 1.01-1.07;P = 0.004)。结论:西班牙裔与未破裂胸腹动脉瘤修复后死亡率增加独立相关。这一发现与术前合并症、术后并发症、外科医生和医院手术量无关。需要进一步的研究来确定这种死亡率差异在指数住院后是否仍然存在。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Racial and ethnic disparities in the treatment of unruptured thoracoabdominal aortic aneurysms in the United States.

Purpose: Previous studies have found increased mortality in minority patients undergoing abdominal aortic aneurysm repair. The goal of this study was to identify racial and ethnic disparities in patients undergoing thoracoabdominal aortic aneurysm repair.

Materials and methods: We queried the Nationwide Inpatient Sample (2005-2009) using International Classification of Diseases, Ninth Revision, Clinical Modification codes for repair of unruptured thoracoabdominal aneurysms. The primary outcome was death. Secondary outcomes included postoperative complications. We performed multivariate analysis adjusting for age, gender, race, comorbidities (Charlson index), insurance type, and surgeon and hospital operative volumes and characteristics.

Results: Overall, 1541 white, 207 black, and 117 Hispanic patients underwent thoracoabdominal aortic aneurysm repair. White patients tended to be older (P = 0.003), whereas black patients had a higher incidence of diabetes mellitus (P = 0.04). Black and Hispanic patients were less likely to have an elective admission (P < 0.001) and more likely to have repair performed at a hospital with a lower average annual surgical volume (P = 0.04). Postoperative complications were similar among the groups (P = 0.31). On multivariate analysis, increased mortality was independently associated with Hispanic ethnicity (relative ratio [RR], 2.57; 95% confidence interval [CI], 1.25-5.25; P = 0.01), cerebrovascular disease (RR, 1.88; 95% CI, 1.10-3.23; P = 0.02), and age (RR, 1.04; 95% CI, 1.01-1.07; P = 0.004).

Conclusions: Hispanic ethnicity is independently associated with increased mortality after repair of unruptured thoracoabdominal aneurysms. This finding was independent of preoperative comorbidities, postoperative complications, and surgeon and hospital operative volumes. Further studies are necessary to determine whether this mortality difference persists after the index hospitalization.

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