医疗植入物感染控制的元胞自动机模型。

IF 0.6 Q4 MATHEMATICS, APPLIED

Applications and Applied Mathematics-An International Journal Pub Date : 2011-06-01

Alicia Prieto-Langarica, Hristo Kojouharov, Benito Chen-Charpentier, Liping Tang

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引用次数: 0

摘要

表皮葡萄球菌感染的医疗植入设备是一个常见的问题，在现代医学由于丰富的细菌。一旦进入体内，表皮葡萄球菌聚集在称为生物膜的群落中，并且可能变得极其难以根除，导致患者严重的并发症。我们模拟复杂的表皮葡萄球菌-中性粒细胞相互作用，以确定免疫系统能够控制感染和避免植入排斥的最佳条件。我们的细胞自动机模型也可以用作确定抗生物膜在医疗植入物上形成的最佳抗生素量的工具。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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A Cellular Automata Model of Infection Control on Medical Implants.

S. epidermidis infections on medically implanted devices are a common problem in modern medicine due to the abundance of the bacteria. Once inside the body, S. epidermidis gather in communities called biofilms and can become extremely hard to eradicate, causing the patient serious complications. We simulate the complex S. epidermidis-Neutrophils interactions in order to determine the optimum conditions for the immune system to be able to contain the infection and avoid implant rejection. Our cellular automata model can also be used as a tool for determining the optimal amount of antibiotics for combating biofilm formation on medical implants.

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来源期刊

Applications and Applied Mathematics-An International Journal MATHEMATICS, APPLIED-

自引率

14.30%

发文量