{"title":"针刺对体外受精结果的影响：一项系统回顾和荟萃分析。","authors":"Fan Qu, Jue Zhou, Ru-Xiang Ren","doi":"10.1089/acm.2011.0158","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>The objective of this article was to conduct a systematic review with meta-analysis of the trials of acupuncture during in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) treatment on the outcomes of clinical pregnancy, biochemical pregnancy, ongoing pregnancy, implantation rate, live birth, and miscarriage.</p><p><strong>Search strategy: </strong>The search was conducted by using MEDLINE(®), SCISEARCH, the Cochrane Menstrual Disorders and Subfertility Group trials register, AMED, Cumulative Index to Nursing and Allied Health Literature, EMBASE, Wanfang Database, China Academic Journal Electronic full text Database in China National Knowledge Infrastructure, Index to Chinese Periodical Literature, ISI Proceedings for conference abstracts, and ISRCTN Register and Meta-register for randomized controlled trials.</p><p><strong>Data collection and analysis: </strong>Study selection, quality appraisal, and data extraction were performed independently and in duplicate. The measures of treatment effect were the pooled relative risks (RR) of achieving clinical pregnancy, biochemical pregnancy, ongoing pregnancy, implantation rate, live birth, or miscarriage for women in the acupuncture group compared with women in the control group.</p><p><strong>Results: </strong>Using the random-effects model, pooling of the effect estimates from all of the 17 trials showed no significant difference in the clinical pregnancy outcome between the acupuncture and the control groups (RR=1.09, 95% confidence interval (CI) 0.94-1.26, p=0.25). No significant differences in the biochemical pregnancy, ongoing pregnancy, implantation rate, live birth, or miscarriage outcomes were found between the acupuncture and the control groups (biochemical pregnancy: RR=1.01, 95% CI 0.84-1.20, p=0.95; ongoing pregnancy: RR=1.20, 95% CI 0.93-1.56, p=0.16; implantation rate: RR=1.22, 95% CI 0.93-1.62, p=0.16; live birth: RR=1.42, 95% CI 0.92-2.20, p=0.11; miscarriage outcomes: RR=0.94, 95% CI 0.67-1.33, p=0.74).</p><p><strong>Conclusions: </strong>No significant benefits of acupuncture are found to improve the outcomes of IVF or ICSI.</p>","PeriodicalId":520659,"journal":{"name":"Journal of alternative and complementary medicine (New York, N.Y.)","volume":" ","pages":"429-39"},"PeriodicalIF":0.0000,"publicationDate":"2012-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Effects of acupuncture on the outcomes of in vitro fertilization: a systematic review and meta-analysis.\",\"authors\":\"Fan Qu, Jue Zhou, Ru-Xiang Ren\",\"doi\":\"10.1089/acm.2011.0158\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objectives: </strong>The objective of this article was to conduct a systematic review with meta-analysis of the trials of acupuncture during in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) treatment on the outcomes of clinical pregnancy, biochemical pregnancy, ongoing pregnancy, implantation rate, live birth, and miscarriage.</p><p><strong>Search strategy: </strong>The search was conducted by using MEDLINE(®), SCISEARCH, the Cochrane Menstrual Disorders and Subfertility Group trials register, AMED, Cumulative Index to Nursing and Allied Health Literature, EMBASE, Wanfang Database, China Academic Journal Electronic full text Database in China National Knowledge Infrastructure, Index to Chinese Periodical Literature, ISI Proceedings for conference abstracts, and ISRCTN Register and Meta-register for randomized controlled trials.</p><p><strong>Data collection and analysis: </strong>Study selection, quality appraisal, and data extraction were performed independently and in duplicate. The measures of treatment effect were the pooled relative risks (RR) of achieving clinical pregnancy, biochemical pregnancy, ongoing pregnancy, implantation rate, live birth, or miscarriage for women in the acupuncture group compared with women in the control group.</p><p><strong>Results: </strong>Using the random-effects model, pooling of the effect estimates from all of the 17 trials showed no significant difference in the clinical pregnancy outcome between the acupuncture and the control groups (RR=1.09, 95% confidence interval (CI) 0.94-1.26, p=0.25). No significant differences in the biochemical pregnancy, ongoing pregnancy, implantation rate, live birth, or miscarriage outcomes were found between the acupuncture and the control groups (biochemical pregnancy: RR=1.01, 95% CI 0.84-1.20, p=0.95; ongoing pregnancy: RR=1.20, 95% CI 0.93-1.56, p=0.16; implantation rate: RR=1.22, 95% CI 0.93-1.62, p=0.16; live birth: RR=1.42, 95% CI 0.92-2.20, p=0.11; miscarriage outcomes: RR=0.94, 95% CI 0.67-1.33, p=0.74).</p><p><strong>Conclusions: </strong>No significant benefits of acupuncture are found to improve the outcomes of IVF or ICSI.</p>\",\"PeriodicalId\":520659,\"journal\":{\"name\":\"Journal of alternative and complementary medicine (New York, N.Y.)\",\"volume\":\" \",\"pages\":\"429-39\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2012-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of alternative and complementary medicine (New York, N.Y.)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1089/acm.2011.0158\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2012/4/27 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of alternative and complementary medicine (New York, N.Y.)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1089/acm.2011.0158","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2012/4/27 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
目的：本文的目的是对体外受精（IVF）或胞浆内单精子注射（ICSI）治疗中针灸对临床妊娠、生化妊娠、持续妊娠、着床率、活产和流产结局的试验进行系统回顾和荟萃分析。检索策略：检索工具为MEDLINE（®）、SCISEARCH、Cochrane月经紊乱与低生育能力组试验注册库、AMED、护理及相关健康文献累积索引、EMBASE、万方数据库、中国国家知识基础设施中国学术期刊电子全文数据库、中国期刊文献索引、ISI会议摘要论文集、ISRCTN随机对照试验注册库和元注册库。数据收集和分析：研究选择、质量评价和数据提取独立进行，一式两份。衡量治疗效果的指标是针灸组妇女与对照组妇女相比临床妊娠、生化妊娠、持续妊娠、着床率、活产、流产的总相对危险度（RR）。结果：采用随机效应模型，对所有17项试验的效应估计进行汇总，针刺组与对照组的临床妊娠结局无显著差异（RR=1.09, 95%可信区间（CI） 0.94 ~ 1.26, p=0.25）。针刺组与对照组在生化妊娠、持续妊娠、着床率、活产、流产结局方面均无显著差异(生化妊娠：RR=1.01, 95% CI 0.84 ~ 1.20, p=0.95；持续妊娠：RR=1.20, 95% CI 0.93-1.56, p=0.16；着床率：RR=1.22, 95% CI 0.93 ~ 1.62, p=0.16；活产：RR=1.42, 95% CI 0.92-2.20, p=0.11；流产结局：RR=0.94, 95% CI 0.67-1.33, p=0.74)。结论：针刺对IVF或ICSI的预后没有明显的改善作用。
Effects of acupuncture on the outcomes of in vitro fertilization: a systematic review and meta-analysis.
Objectives: The objective of this article was to conduct a systematic review with meta-analysis of the trials of acupuncture during in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) treatment on the outcomes of clinical pregnancy, biochemical pregnancy, ongoing pregnancy, implantation rate, live birth, and miscarriage.
Search strategy: The search was conducted by using MEDLINE(®), SCISEARCH, the Cochrane Menstrual Disorders and Subfertility Group trials register, AMED, Cumulative Index to Nursing and Allied Health Literature, EMBASE, Wanfang Database, China Academic Journal Electronic full text Database in China National Knowledge Infrastructure, Index to Chinese Periodical Literature, ISI Proceedings for conference abstracts, and ISRCTN Register and Meta-register for randomized controlled trials.
Data collection and analysis: Study selection, quality appraisal, and data extraction were performed independently and in duplicate. The measures of treatment effect were the pooled relative risks (RR) of achieving clinical pregnancy, biochemical pregnancy, ongoing pregnancy, implantation rate, live birth, or miscarriage for women in the acupuncture group compared with women in the control group.
Results: Using the random-effects model, pooling of the effect estimates from all of the 17 trials showed no significant difference in the clinical pregnancy outcome between the acupuncture and the control groups (RR=1.09, 95% confidence interval (CI) 0.94-1.26, p=0.25). No significant differences in the biochemical pregnancy, ongoing pregnancy, implantation rate, live birth, or miscarriage outcomes were found between the acupuncture and the control groups (biochemical pregnancy: RR=1.01, 95% CI 0.84-1.20, p=0.95; ongoing pregnancy: RR=1.20, 95% CI 0.93-1.56, p=0.16; implantation rate: RR=1.22, 95% CI 0.93-1.62, p=0.16; live birth: RR=1.42, 95% CI 0.92-2.20, p=0.11; miscarriage outcomes: RR=0.94, 95% CI 0.67-1.33, p=0.74).
Conclusions: No significant benefits of acupuncture are found to improve the outcomes of IVF or ICSI.
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