慢性腹膜透析对有特殊需要或社会劣势或两者兼而有之的儿童:禁忌症并不总是禁忌症。

Nejat Aksu, Onder Yavascan, Murat Anil, Orhan Deniz Kara, Alkan Bal, Ayse Berna Anil
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引用次数: 14

摘要

目的:本研究的目的是确定在儿科透析病房接受慢性腹膜透析(CPD)治疗的有特殊需要或社会劣势的儿童的结局。方法:在1995年11月至2008年11月期间,在我单位开始CPD的110名儿童中,我们确定了13名患者(8名女孩,5名男孩)有严重的身体,精神或社会心理问题。残疾组开始CPD的年龄从4.0岁到16.5岁(中位数:7.5岁)。以下疾病为膀胱输尿管反流(4例)、神经性膀胱及膀胱输尿管反流(3例)、慢性肾盂肾炎(3例)、淀粉样变(2例)、Alport综合征(1例)。遇到的挑战包括不良的家庭或社会环境(4例),脑瘫(3例),唐氏综合征(1例),直肠膀胱瘘合并异位肛门和既往多次腹部手术(1例),失明和耳聋(1例),脑室-腹膜分流术(1例),结肠造口和营养不良(1例),智力低下和失明(1例)。所有导管均经皮植入。结果:透析持续时间中位数为18个月(范围:6 - 124个月)。残疾儿童与非残疾儿童腹膜炎发生率无显著性差异(p > 0.05)。残疾儿童与无残疾儿童相比,导管相关感染(1次/79.3例患者-月vs 1次/32.4例患者-月)和导管相关非感染性并发症(1次/238例患者-月vs 1次/115.7例患者-月)的发生率较低(p < 0.05)。5例儿童终止慢性腹膜透析(3例为肾移植,1例转为血液透析,1例死亡)。结论:我们的研究结果表明,在适当的家庭支持和经验丰富的多学科团队的帮助下,CPD可以有效地用于有特殊需要或社会弱势的儿童,或两者兼有。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Chronic peritoneal dialysis in children with special needs or social disadvantage or both: contraindications are not always contraindications.

Objective: Our aim in the present study was to identify outcomes in children with special needs or social disadvantage, or both, receiving chronic peritoneal dialysis (CPD) treatment in a pediatric dialysis unit.

Methods: Among 110 children started on CPD in our unit during the period between November 1995 and November 2008, we identified 13 patients (8 girls, 5 boys) with major physical, mental, or psychosocial problems. Age at CPD initiation in the group with disability ranged from 4.0 years to 16.5 years (median: 7.5 years). Under lying diseases were vesicoureteral reflux (4 patients), neuropathic bladder and vesicoureteral reflux (3 patients), chronic pyelonephritis (3 patients), amyloidosis (2 patients), and Alport syndrome (1 patient). Challenges encountered were adverse family or social circumstances (4 patients), cerebral palsy (3 patients), Down syndrome (1 patient), rectovesical fistula in conjunction with ectopic anus and previous multiple abdominal surgery (1 patient), blindness and deafness (1 patient), ventriculoperitoneal shunt (1 patient), colostomy and malnutrition (1 patient), and mental retardation and blindness (1 patient). All catheters were implanted percutaneously.

Results: Median duration of dialysis was 18 months (range: 6 - 124 months). The frequency of peritonitis was not different between children with and without disability (p > 0.05). In children with disability compared with children without disability, the frequencies of catheter-related infections (1 episode/79.3 patient-months vs 1 episode/32.4 patient-months) and of catheter-related non-infectious complications (1 episode/238 patient-months vs 1 episode/115.7 patient-months) were lower (p < 0.05). Chronic peritoneal dialysis was terminated in 5 children (for renal transplantation in 3, switch to hemodialysis in 1, death in 1).

Conclusions: Our results suggest that, with appropriate family support and an experienced multidisciplinary team, CPD can be effectively performed in children with special needs or social disadvantage, or both.

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