泰国药房治疗急性感染性腹泻的药物选择:一项定性研究。

IF 1.1 Q4 PHARMACOLOGY & PHARMACY
Translational and Clinical Pharmacology Pub Date : 2021-12-01 Epub Date: 2021-12-16 DOI:10.12793/tcp.2021.29.e22
Nattawut Leelakanok, Arpa Petchsomrit, Janthima Methaneethorn, Suphannika Prateepjarassaeng Pornwattanakavee
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引用次数: 0

摘要

世界卫生组织(WHO)于 2005 年发布了腹泻治疗手册。我们的目的是调查泰国社区药房在选择治疗急性感染性腹泻药物时的依据,以及选择的药物是否符合世界卫生组织的手册。我们采访了一名理论上患有急性感染性腹泻的 18 岁患者。研究方案和材料已获得机构审查委员会批准。通过便利抽样法共选取了 30 名药店工作人员,并将其纳入研究范围。第一作者对访谈记录进行了人工编码、主题提取和翻译。参与者认为腹泻并不严重,因此没有发放口服补液盐。之所以配发吸附剂,是因为他们认为吸附剂是治疗非感染性腹泻或轻度腹泻的一线药物。配发抗生素是因为担心预后和病人的预期压力。由于不了解锌的适应症,没有人向患者提供锌。我们发现,泰国药店对急性感染性腹泻的配药偏离了世界卫生组织的治疗指南。究其原因,主要是药剂师没有遵循循证医学原则、缺乏相关知识、患者压力大、产品供应不足以及当地指南中的信息可感知性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Medication selection for the treatment of acute infective diarrhea in Thai pharmacies: a qualitative study.

Medication selection for the treatment of acute infective diarrhea in Thai pharmacies: a qualitative study.

Medication selection for the treatment of acute infective diarrhea in Thai pharmacies: a qualitative study.

Medication selection for the treatment of acute infective diarrhea in Thai pharmacies: a qualitative study.

World Health Organization (WHO) released the treatment manual of diarrhea in 2005. We aimed to investigate the rationale for selecting medications for acute infective diarrhea in Thai community pharmacies and to see if the selection complied with the WHO manual. A theoretical 18-year-old patient with acute infective diarrhea was used for interviews. The protocol and materials for the research were approved by Institutional Review Board. A total of 30 drugstore personnel were selected by convenience sampling and included. The first author manually coded, extracted for themes, and translated the transcript. Participants did not dispense oral rehydration salt because of the feeling that diarrhea was not severe. Absorbents were dispensed because they were perceived as the first-line medication for noninfective or mild diarrhea. Antibiotics were dispensed because of the concerns for the prognosis and the expected patient pressure. None provided zinc to the patient because of the lack of knowledge of the indication of zinc. We found that dispensing for acute infective diarrhea in Thai drugstores deviated from the WHO treatment guideline. The reasons were that the pharmacy personnel were not practicing evidence-based medicine, the lack of knowledge, the patient pressure, the unavailability of products, and the perceived availability of information in local guidelines.

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来源期刊
Translational and Clinical Pharmacology
Translational and Clinical Pharmacology Medicine-Pharmacology (medical)
CiteScore
1.60
自引率
11.10%
发文量
17
期刊介绍: Translational and Clinical Pharmacology (Transl Clin Pharmacol, TCP) is the official journal of the Korean Society for Clinical Pharmacology and Therapeutics (KSCPT). TCP is an interdisciplinary journal devoted to the dissemination of knowledge relating to all aspects of translational and clinical pharmacology. The categories for publication include pharmacokinetics (PK) and drug disposition, drug metabolism, pharmacodynamics (PD), clinical trials and design issues, pharmacogenomics and pharmacogenetics, pharmacometrics, pharmacoepidemiology, pharmacovigilence, and human pharmacology. Studies involving animal models, pharmacological characterization, and clinical trials are appropriate for consideration.
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