维生素C在COVID-19治疗中的保护作用综述

Q1 Nursing
Mohammad Sarowar Uddin, Md Shalahuddin Millat, Prodip Kumar Baral, Mahmuda Ferdous, Md Giash Uddin, Md Shahid Sarwar, Mohammad Safiqul Islam
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引用次数: 10

摘要

背景:2019冠状病毒感染疾病(COVID-19)的爆发在全球范围内被认为是对人类生命的重大威胁。研究人员正在寻找预防策略、缓解干预措施和可能降低感染严重程度的潜在治疗方法。其中一个在网络和社交媒体上被高度讨论的方法是维生素C。主要内容:维生素C是一种强大的抗氧化剂,可以增强人体的免疫系统。它有助于正常的中性粒细胞功能、氧化物质的清除、维生素E的再生、信号通路的调节、促炎转录因子的激活、信号级联的激活、炎症介质的调节和吞噬,并增加中性粒细胞向感染部位的运动。所有这些免疫功能都是预防COVID-19感染所必需的。结论:考虑到维生素C的作用,对重症COVID-19患者给予维生素C治疗势在必行。然而,目前尚无具体的临床数据证实在本次大流行中使用了维生素C。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

The protective role of vitamin C in the management of COVID-19: A Review.

The protective role of vitamin C in the management of COVID-19: A Review.

The protective role of vitamin C in the management of COVID-19: A Review.

Background: The outbreak of coronavirus infectious disease-2019 (COVID-19) is globally deemed a significant threat to human life. Researchers are searching for prevention strategies, mitigation interventions, and potential therapeutics that may reduce the infection's severity. One such means that is highly being talked in online and in social media is vitamin C.

Main text: Vitamin C is a robust antioxidant that boosts the immune system of the human body. It helps in normal neutrophil function, scavenging of oxidative species, regeneration of vitamin E, modulation of signaling pathways, activation of pro-inflammatory transcription factors, activation of the signaling cascade, regulation of inflammatory mediators, and phagocytosis and increases neutrophil motility to the site of infection. All of these immunological functions are required for the prevention of COVID-19 infection.

Conclusion: Considering the role of vitamin C, it would be imperative to administrate vitamin C for the management of severe COVID-19. However, there is no specific clinical data available to confirm the use of vitamin C in the current pandemic.

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来源期刊
CiteScore
6.50
自引率
0.00%
发文量
25
审稿时长
10 weeks
期刊介绍: The journal accepts papers of original research which are not being considered for publication elsewhere and which contribute to the advancement of knowledge of Public Health at large
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