COVID-19患者诊断和管理的实验室生物标志物:最新综述

IF 2 4区 医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL
Discovery medicine Pub Date : 2021-03-01
Bin-Bin Li, Sheng-Jie Huang, Yi-Long Fu, Zhong-Lin Li, Juan Wang, Jin-Long Wang
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引用次数: 0

摘要

严重急性呼吸综合征冠状病毒-2 (SARS-CoV-2)因其传染性强、传播速度快,已成为全球性危机。部分2019冠状病毒病(COVID-19)患者进展迅速,并可能出现致命性并发症,这给疾病评估和治疗带来了严峻挑战。最近对SARS-CoV-2分子生物学的理解取得了进展,导致鉴定出多种实验室生物标志物,这些生物标志物可能潜在地应用于临床实践,用于COVID-19患者的诊断、治疗和预后。本文综述了新冠肺炎相关实验室标志物鉴定的最新进展,并提出了新冠肺炎相关标志物在临床诊断和治疗中的应用方向。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Laboratory Biomarkers for the Diagnosis and Management of Patients with COVID-19: an Updated Review.

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has become a global crisis due to strong infectivity and fast transmission speed. Some patients with Coronavirus Disease 2019 (COVID-19) progress rapidly and may develop fatal complications, which brings serious challenges in disease assessment and treatment. Recent progress in the understanding of the molecular biology of SARS-CoV-2 has led to the identification of a variety of laboratory biomarkers that could be potentially applied to clinical practice for the diagnosis, treatment, and prognosis of patients with COVID-19. In this review we summarize the updated status on the identification of COVID-19 related laboratory markers, and propose further direction on the application of these markers to clinical diagnosis and management of patients with COVID-19.

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来源期刊
Discovery medicine
Discovery medicine MEDICINE, RESEARCH & EXPERIMENTAL-
CiteScore
5.40
自引率
0.00%
发文量
80
审稿时长
6-12 weeks
期刊介绍: Discovery Medicine publishes novel, provocative ideas and research findings that challenge conventional notions about disease mechanisms, diagnosis, treatment, or any of the life sciences subjects. It publishes cutting-edge, reliable, and authoritative information in all branches of life sciences but primarily in the following areas: Novel therapies and diagnostics (approved or experimental); innovative ideas, research technologies, and translational research that will give rise to the next generation of new drugs and therapies; breakthrough understanding of mechanism of disease, biology, and physiology; and commercialization of biomedical discoveries pertaining to the development of new drugs, therapies, medical devices, and research technology.
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