{"title":"土耳其重症监护病房974例COVID-19患者的特征和结局","authors":"Hülya Sungurtekin, Cansu Ozgen, Ulku Arslan, Kemal Tolga Saracoglu, Volkan Yarar, Ahmet Sari, Ayse Turan Civraz, Ali Aydin Altunkan, Hilal Ayoglu, Nilgun Kavrut Ozturk, Nihal Bulut Yuksel, Birgul Yelken, Elif Bombaci, Gokhan Kilinc, Damla Akman, Pinar Demir, Ferruh Ayoglu, Fulya Ciyiltepe, Ahmet Caliskan, Simay Karaduman","doi":"10.5144/0256-4947.2021.318","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>In our previous report on Turkish COVID-19 patients requiring intensive care, the 24 patients in a single ICU were elderly and mortality was high. We extended our analysis to include patients admitted to ten ICUs.</p><p><strong>Objectives: </strong>Report the demographics, clinical features, imaging findings, comorbidities, and outcomes in COVID-19 patients.</p><p><strong>Design: </strong>Retrospective.</p><p><strong>Setting: </strong>Intensive care unit.</p><p><strong>Patients and methods: </strong>The study includes patients with clinical and radiological confirmed or laboratory-confirmed COVID-19 infection who were admitted to ten ICUs between 15 March and 30 June 2020.</p><p><strong>Main outcome measures: </strong>Clinical outcomes, therapies, and death during hospitalization SAMPLE SIZE: 974, including 571 males (58%).</p><p><strong>Results: </strong>The median age (range) was 72 (21-101) years for patients who died (n=632, 64.9%) and 70 (16-99) years for patients who lived (n=432, 35.2%) (<i>P</i><.001). APACHE scores, and SOFA scores were higher in patients who died than in those who survived (<i>P</i><.001, both comparisons). Respiratory failure was the most common cause of hospitalization (82.5%), and respiratory failure on admission was associated with death (<i>P</i>=.013). Most (n=719, 73.8%) underwent invasive mechanical ventilation therapy.</p><p><strong>Conclusions: </strong>The majority of patients admitted to the ICU with a diagnosis of COVID-19 require respiratory support.</p><p><strong>Limitations: </strong>Although the Turkish Ministry of Health made recommendations for the treatment of COVID-19 patients, patient management may not have been identical in all ten units.</p><p><strong>Conflict of interest: </strong>None.</p>","PeriodicalId":8016,"journal":{"name":"Annals of Saudi Medicine","volume":"41 6","pages":"318-326"},"PeriodicalIF":1.5000,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0b/5f/0256-4947.2021.318.PMC8650594.pdf","citationCount":"3","resultStr":"{\"title\":\"Characteristics and outcomes of 974 COVID-19 patients in intensive care units in Turkey.\",\"authors\":\"Hülya Sungurtekin, Cansu Ozgen, Ulku Arslan, Kemal Tolga Saracoglu, Volkan Yarar, Ahmet Sari, Ayse Turan Civraz, Ali Aydin Altunkan, Hilal Ayoglu, Nilgun Kavrut Ozturk, Nihal Bulut Yuksel, Birgul Yelken, Elif Bombaci, Gokhan Kilinc, Damla Akman, Pinar Demir, Ferruh Ayoglu, Fulya Ciyiltepe, Ahmet Caliskan, Simay Karaduman\",\"doi\":\"10.5144/0256-4947.2021.318\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>In our previous report on Turkish COVID-19 patients requiring intensive care, the 24 patients in a single ICU were elderly and mortality was high. We extended our analysis to include patients admitted to ten ICUs.</p><p><strong>Objectives: </strong>Report the demographics, clinical features, imaging findings, comorbidities, and outcomes in COVID-19 patients.</p><p><strong>Design: </strong>Retrospective.</p><p><strong>Setting: </strong>Intensive care unit.</p><p><strong>Patients and methods: </strong>The study includes patients with clinical and radiological confirmed or laboratory-confirmed COVID-19 infection who were admitted to ten ICUs between 15 March and 30 June 2020.</p><p><strong>Main outcome measures: </strong>Clinical outcomes, therapies, and death during hospitalization SAMPLE SIZE: 974, including 571 males (58%).</p><p><strong>Results: </strong>The median age (range) was 72 (21-101) years for patients who died (n=632, 64.9%) and 70 (16-99) years for patients who lived (n=432, 35.2%) (<i>P</i><.001). APACHE scores, and SOFA scores were higher in patients who died than in those who survived (<i>P</i><.001, both comparisons). Respiratory failure was the most common cause of hospitalization (82.5%), and respiratory failure on admission was associated with death (<i>P</i>=.013). Most (n=719, 73.8%) underwent invasive mechanical ventilation therapy.</p><p><strong>Conclusions: </strong>The majority of patients admitted to the ICU with a diagnosis of COVID-19 require respiratory support.</p><p><strong>Limitations: </strong>Although the Turkish Ministry of Health made recommendations for the treatment of COVID-19 patients, patient management may not have been identical in all ten units.</p><p><strong>Conflict of interest: </strong>None.</p>\",\"PeriodicalId\":8016,\"journal\":{\"name\":\"Annals of Saudi Medicine\",\"volume\":\"41 6\",\"pages\":\"318-326\"},\"PeriodicalIF\":1.5000,\"publicationDate\":\"2021-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0b/5f/0256-4947.2021.318.PMC8650594.pdf\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annals of Saudi Medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.5144/0256-4947.2021.318\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2021/12/2 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of Saudi Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.5144/0256-4947.2021.318","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2021/12/2 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Characteristics and outcomes of 974 COVID-19 patients in intensive care units in Turkey.
Background: In our previous report on Turkish COVID-19 patients requiring intensive care, the 24 patients in a single ICU were elderly and mortality was high. We extended our analysis to include patients admitted to ten ICUs.
Objectives: Report the demographics, clinical features, imaging findings, comorbidities, and outcomes in COVID-19 patients.
Design: Retrospective.
Setting: Intensive care unit.
Patients and methods: The study includes patients with clinical and radiological confirmed or laboratory-confirmed COVID-19 infection who were admitted to ten ICUs between 15 March and 30 June 2020.
Main outcome measures: Clinical outcomes, therapies, and death during hospitalization SAMPLE SIZE: 974, including 571 males (58%).
Results: The median age (range) was 72 (21-101) years for patients who died (n=632, 64.9%) and 70 (16-99) years for patients who lived (n=432, 35.2%) (P<.001). APACHE scores, and SOFA scores were higher in patients who died than in those who survived (P<.001, both comparisons). Respiratory failure was the most common cause of hospitalization (82.5%), and respiratory failure on admission was associated with death (P=.013). Most (n=719, 73.8%) underwent invasive mechanical ventilation therapy.
Conclusions: The majority of patients admitted to the ICU with a diagnosis of COVID-19 require respiratory support.
Limitations: Although the Turkish Ministry of Health made recommendations for the treatment of COVID-19 patients, patient management may not have been identical in all ten units.
期刊介绍：
The Annals of Saudi Medicine (ASM) is published bimonthly by King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia. We publish scientific reports of clinical interest in English. All submissions are subject to peer review by the editorial board and by reviewers in appropriate specialties. The journal will consider for publication manuscripts from any part of the world, but particularly reports that would be of interest to readers in the Middle East or other parts of Asia and Africa. Please go to the Author Resource Center for additional information.
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