Mir Sadat-Ali, Abdallah S AlOmran, Sulaiman A AlMousa, Hasan N AlSayed, Khalid W AlTabash, Mohammed Q Azam, Tarek M Hegazi, Sadananda Acharya
{"title":"自体骨髓来源的软骨细胞治疗膝骨关节炎:一项随机对照试验。","authors":"Mir Sadat-Ali, Abdallah S AlOmran, Sulaiman A AlMousa, Hasan N AlSayed, Khalid W AlTabash, Mohammed Q Azam, Tarek M Hegazi, Sadananda Acharya","doi":"10.1155/2021/2146722","DOIUrl":null,"url":null,"abstract":"<p><strong>Results: </strong>There were a total of 60 patients who were followed up. Three patients in Group II were removed from the analysis as they underwent total knee arthroplasty (TKA). A notably significant improvement was noticed in the ABMDC group on all scores of VAS and MKSSSF with <i>P</i> < 0.0001. The control group continued to be dissatisfied with the treatment they were taking.</p><p><strong>Conclusions: </strong>This study reveals that a single injection of 5 million of ABMDC was efficient in reducing the symptoms, improving the functional score and betterment of QOL.</p>","PeriodicalId":7358,"journal":{"name":"Advances in Orthopedics","volume":"2021 ","pages":"2146722"},"PeriodicalIF":1.2000,"publicationDate":"2021-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627347/pdf/","citationCount":"1","resultStr":"{\"title\":\"Autologous Bone Marrow-Derived Chondrocytes for Patients with Knee Osteoarthritis: A Randomized Controlled Trial.\",\"authors\":\"Mir Sadat-Ali, Abdallah S AlOmran, Sulaiman A AlMousa, Hasan N AlSayed, Khalid W AlTabash, Mohammed Q Azam, Tarek M Hegazi, Sadananda Acharya\",\"doi\":\"10.1155/2021/2146722\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Results: </strong>There were a total of 60 patients who were followed up. Three patients in Group II were removed from the analysis as they underwent total knee arthroplasty (TKA). A notably significant improvement was noticed in the ABMDC group on all scores of VAS and MKSSSF with <i>P</i> < 0.0001. The control group continued to be dissatisfied with the treatment they were taking.</p><p><strong>Conclusions: </strong>This study reveals that a single injection of 5 million of ABMDC was efficient in reducing the symptoms, improving the functional score and betterment of QOL.</p>\",\"PeriodicalId\":7358,\"journal\":{\"name\":\"Advances in Orthopedics\",\"volume\":\"2021 \",\"pages\":\"2146722\"},\"PeriodicalIF\":1.2000,\"publicationDate\":\"2021-11-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627347/pdf/\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Advances in Orthopedics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1155/2021/2146722\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2021/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"ORTHOPEDICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advances in Orthopedics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/2021/2146722","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2021/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"ORTHOPEDICS","Score":null,"Total":0}
Autologous Bone Marrow-Derived Chondrocytes for Patients with Knee Osteoarthritis: A Randomized Controlled Trial.
Results: There were a total of 60 patients who were followed up. Three patients in Group II were removed from the analysis as they underwent total knee arthroplasty (TKA). A notably significant improvement was noticed in the ABMDC group on all scores of VAS and MKSSSF with P < 0.0001. The control group continued to be dissatisfied with the treatment they were taking.
Conclusions: This study reveals that a single injection of 5 million of ABMDC was efficient in reducing the symptoms, improving the functional score and betterment of QOL.
期刊介绍:
Advances in Orthopedics is a peer-reviewed, Open Access journal that provides a forum for orthopaedics working on improving the quality of orthopedic health care. The journal publishes original research articles, review articles, and clinical studies related to arthroplasty, hand surgery, limb reconstruction, pediatric orthopaedics, sports medicine, trauma, spinal deformities, and orthopaedic oncology.