James A Platts-Mills, Elias G Ayoub, Jixian Zhang, Elizabeth T Rogawski McQuade, Ahmed M Arzika, Ramatou Maliki, Amza Abdou, Jeremy D Keenan, Thomas M Lietman, Jie Liu, Eric R Houpt
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Impact of Biannual Mass Azithromycin Treatment on Enteropathogen Carriage in Children <5 Years Old in Niger.
We analyzed samples obtained at baseline and 24 months in a mass azithromycin administration trial in Niger using quantitative polymerase chain reaction. In villages randomized to azithromycin, Shigella was the only pathogen reduced at 24 months (prevalence ratio, 0.36 [95% confidence interval: .17-.79]; difference in log quantity, -.42 [-.75 to -.10]).
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