Samirah Alshehri, John Prior, Mohammed Moshebah, Luis Schiappacasse, Vincent Dunet
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引用次数: 0
摘要
使用O-(2-[18F]氟乙基)- l -酪氨酸(18F- fet)的正电子发射断层扫描(PET)已被证明是鉴别放射治疗结果的有用工具，如脑转移复发或放射性坏死。我们报告一位女性肺黏液腺癌脑转移患者，在放射手术后复查核磁共振成像(MRI)时怀疑肿瘤复发。18F-FET PET/ CT提示放射性坏死。由于患者病史及脑MRI与PET/CT结果不一致，决定行手术活检，脑转移复发阳性。在18F-FET PET/CT上诊断转移性复发也可能具有挑战性。如果MRI和PET/CT结果不一致，仍有可能出现18F-FET PET/CT假阴性，需要仔细随访或活检。
Negative 18F-FET PET/CT in brain metastasis recurrence: a teaching case report.
Positron emission tomography (PET) using O-(2-[18F]fluoroethyl)-L-tyrosine (18F-FET) PET has been shown to be a useful tool for differentiating radiation therapy outcomes, such as brain metastasis recurrence or radiation necrosis. We present the case of a female patient with brain metastases from pulmonary mucinous adenocarcinoma with suspicion of tumor recurrence on follow-up magnetic resonance imaging (MRI) after radiosurgery. 18F-FET PET/computed tomography (CT) was indicative of radiation necrosis. Due to the patient's medical history and the discrepancy between the brain MRI and PET/CT results, surgical biopsies were decided, which were positive for brain metastasis recurrence. The diagnosis of metastasis recurrence may also be challenging on 18F-FET PET/CT. In case of discrepancies between MRI and PET/CT results, false-negative 18F-FET PET/CT remains a possibility and requires careful follow-up or biopsy.
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