为 COVID-19 感染、住院和死亡的本地建模建立基于 SEIR 的框架。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Accounts of Chemical Research Pub Date : 2021-09-06 eCollection Date: 2021-01-01 DOI:10.1080/20476965.2021.1973348
R M Wood, A C Pratt, B J Murch, A L Powell, R D Booton, D G Thomas, J Twigger, E Diakou, S Coleborn, T Manning, C Davies, K M Turner
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引用次数: 0

摘要

如果不能及时评估需要住院治疗的 COVID-19 病例数量,医疗服务提供者将很难确保提供适当数量的病床。病床太少可能会导致过多的死亡,而病床太多又可能导致需要等待更多的选择性治疗。除了支持能力方面的考虑外,可靠地预测未来的 "浪潮 "也很重要,这有助于确定任何旨在减少传播的地方限制措施的性质、时间和规模。本文详细介绍了一家大型医疗保健系统在建立由专员、公共卫生官员和学术流行病学家组成的多学科 "情景审查工作组 "时所采用的方法,以说明地方自主和地方可配置模型的重要性。该工作组在大流行期间每周召开一次会议,其职责是定义和维护一个不断发展的合理情景库,以支持通过基于 SEIR 的分区模型获得的预测结果。其结果为系统中重大事件铜牌、银牌和金牌指挥部的决策提供了依据。本文举例说明了这一框架的使用情况,并为其他可能受益于这一框架的医疗保健系统提供了实用的考虑因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Establishing an SEIR-based framework for local modelling of COVID-19 infections, hospitalisations and deaths.

Establishing an SEIR-based framework for local modelling of COVID-19 infections, hospitalisations and deaths.

Without timely assessments of the number of COVID-19 cases requiring hospitalisation, healthcare providers will struggle to ensure an appropriate number of beds are made available. Too few could cause excess deaths while too many could result in additional waits for elective treatment. As well as supporting capacity considerations, reliably projecting future "waves" is important to inform the nature, timing and magnitude of any localised restrictions to reduce transmission. In making the case for locally owned and locally configurable models, this paper details the approach taken by one major healthcare system in founding a multi-disciplinary "Scenario Review Working Group", comprising commissioners, public health officials and academic epidemiologists. The role of this group, which met weekly during the pandemic, was to define and maintain an evolving library of plausible scenarios to underpin projections obtained through an SEIR-based compartmental model. Outputs have informed decision-making at the system's major incident Bronze, Silver and Gold Commands. This paper presents illustrated examples of use and offers practical considerations for other healthcare systems that may benefit from such a framework.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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