{"title":"心力衰竭后的死亡率和再入院率:系统回顾和荟萃分析。","authors":"Tian Lan, Yan-Hui Liao, Jian Zhang, Zhi-Ping Yang, Gao-Si Xu, Liang Zhu, Dai-Ming Fan","doi":"10.2147/TCRM.S340587","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>The current work aimed to examine the rates of and risk factors for mortality and readmission after heart failure (HF).</p><p><strong>Setting: </strong>A systematic search was carried out in PubMed, the Cochrane Library, and EMBASE to identify eligible reports. The random-effects model was utilized to evaluate the pooled results.</p><p><strong>Participants: </strong>A total of 27 studies with 515,238 participants were finally meta-analysed. The HF patients had an average age of 76.3 years, with 51% of the sample being male, in the pooled analysis.</p><p><strong>Primary and secondary outcome measures: </strong>The outcome measures were 30-day and 1-year readmission rates, mortality, and risk factors for readmission and mortality.</p><p><strong>Results: </strong>The effect sizes for readmission and mortality were estimated as the mean and 95% confidence interval (CI). The estimated 30-day and 1-year all-cause readmission rates were 0.19 (95% CI 0.14-0.23) and 0.53 (95% CI 0.46-0.59), respectively, while the all-cause mortality rates were 0.14 (95% CI 0.10-0.18) and 0.29 (95% CI 0.25-0.33), respectively. Comorbidities were highly prevalent in individuals with HF.</p><p><strong>Conclusion: </strong>Heart failure hospitalization is followed by high readmission and mortality rates.</p>","PeriodicalId":48769,"journal":{"name":"Therapeutics and Clinical Risk Management","volume":null,"pages":null},"PeriodicalIF":2.3000,"publicationDate":"2021-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3c/38/tcrm-17-1307.PMC8665875.pdf","citationCount":"8","resultStr":"{\"title\":\"Mortality and Readmission Rates After Heart Failure: A Systematic Review and Meta-Analysis.\",\"authors\":\"Tian Lan, Yan-Hui Liao, Jian Zhang, Zhi-Ping Yang, Gao-Si Xu, Liang Zhu, Dai-Ming Fan\",\"doi\":\"10.2147/TCRM.S340587\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>The current work aimed to examine the rates of and risk factors for mortality and readmission after heart failure (HF).</p><p><strong>Setting: </strong>A systematic search was carried out in PubMed, the Cochrane Library, and EMBASE to identify eligible reports. The random-effects model was utilized to evaluate the pooled results.</p><p><strong>Participants: </strong>A total of 27 studies with 515,238 participants were finally meta-analysed. The HF patients had an average age of 76.3 years, with 51% of the sample being male, in the pooled analysis.</p><p><strong>Primary and secondary outcome measures: </strong>The outcome measures were 30-day and 1-year readmission rates, mortality, and risk factors for readmission and mortality.</p><p><strong>Results: </strong>The effect sizes for readmission and mortality were estimated as the mean and 95% confidence interval (CI). The estimated 30-day and 1-year all-cause readmission rates were 0.19 (95% CI 0.14-0.23) and 0.53 (95% CI 0.46-0.59), respectively, while the all-cause mortality rates were 0.14 (95% CI 0.10-0.18) and 0.29 (95% CI 0.25-0.33), respectively. Comorbidities were highly prevalent in individuals with HF.</p><p><strong>Conclusion: </strong>Heart failure hospitalization is followed by high readmission and mortality rates.</p>\",\"PeriodicalId\":48769,\"journal\":{\"name\":\"Therapeutics and Clinical Risk Management\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2021-12-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3c/38/tcrm-17-1307.PMC8665875.pdf\",\"citationCount\":\"8\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Therapeutics and Clinical Risk Management\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.2147/TCRM.S340587\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2021/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q2\",\"JCRName\":\"HEALTH CARE SCIENCES & SERVICES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Therapeutics and Clinical Risk Management","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.2147/TCRM.S340587","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2021/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"HEALTH CARE SCIENCES & SERVICES","Score":null,"Total":0}
引用次数: 8
摘要
目的:本研究旨在探讨心力衰竭(HF)后死亡率和再入院率及其危险因素。环境:在PubMed、Cochrane图书馆和EMBASE中进行系统搜索，以确定符合条件的报告。采用随机效应模型对合并结果进行评价。参与者:共有27项研究，515,238名参与者最终进行了meta分析。在合并分析中，HF患者的平均年龄为76.3岁，51%的样本为男性。主要和次要结局指标:结局指标为30天和1年再入院率、死亡率、再入院和死亡率的危险因素。结果:再入院和死亡率的效应量以平均值和95%置信区间(CI)估计。估计30天和1年的全因再入院率分别为0.19 (95% CI 0.14-0.23)和0.53 (95% CI 0.46-0.59)，而全因死亡率分别为0.14 (95% CI 0.10-0.18)和0.29 (95% CI 0.25-0.33)。合并症在心衰患者中非常普遍。结论:心力衰竭住院后再入院率高，死亡率高。
Mortality and Readmission Rates After Heart Failure: A Systematic Review and Meta-Analysis.
Objective: The current work aimed to examine the rates of and risk factors for mortality and readmission after heart failure (HF).
Setting: A systematic search was carried out in PubMed, the Cochrane Library, and EMBASE to identify eligible reports. The random-effects model was utilized to evaluate the pooled results.
Participants: A total of 27 studies with 515,238 participants were finally meta-analysed. The HF patients had an average age of 76.3 years, with 51% of the sample being male, in the pooled analysis.
Primary and secondary outcome measures: The outcome measures were 30-day and 1-year readmission rates, mortality, and risk factors for readmission and mortality.
Results: The effect sizes for readmission and mortality were estimated as the mean and 95% confidence interval (CI). The estimated 30-day and 1-year all-cause readmission rates were 0.19 (95% CI 0.14-0.23) and 0.53 (95% CI 0.46-0.59), respectively, while the all-cause mortality rates were 0.14 (95% CI 0.10-0.18) and 0.29 (95% CI 0.25-0.33), respectively. Comorbidities were highly prevalent in individuals with HF.
Conclusion: Heart failure hospitalization is followed by high readmission and mortality rates.
期刊介绍：
Therapeutics and Clinical Risk Management is an international, peer-reviewed journal of clinical therapeutics and risk management, focusing on concise rapid reporting of clinical studies in all therapeutic areas, outcomes, safety, and programs for the effective, safe, and sustained use of medicines, therapeutic and surgical interventions in all clinical areas.
The journal welcomes submissions covering original research, clinical and epidemiological studies, reviews, guidelines, expert opinion and commentary. The journal will consider case reports but only if they make a valuable and original contribution to the literature.
As of 18th March 2019, Therapeutics and Clinical Risk Management will no longer consider meta-analyses for publication.
The journal does not accept study protocols, animal-based or cell line-based studies.
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