组学技术在心血管疾病个性化联合治疗中的应用:挑战与机遇。

IF 1.7 4区医学 Q3 PHARMACOLOGY & PHARMACY

Personalized medicine Pub Date : 2021-09-01 Epub Date: 2021-10-25 DOI:10.2217/pme-2021-0087

Saradindu Banerjee, Navya Prabhu Basrur, Padmalatha S Rai

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引用次数: 3

摘要

“组学”技术的主要目的是了解基因组学、蛋白质组学、代谢组学和其他分子机制的复杂性，以揭示人类疾病的复杂特征。组学技术的大量使用及其在医学上的应用加快了对几种疾病发病机制的研究。在疾病早期检测生物标志物具有挑战性;然而，组学可以发现新的分子机制和生物标志物。本文综述了不同类型的组学及其技术，旨在为其在心血管精准医学中的应用提供参考。这些技术显著影响优化医疗个人达到更高水平的精准医疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Omics technologies in personalized combination therapy for cardiovascular diseases: challenges and opportunities.

The primary purpose of 'omics' technologies is to understand the intricacy of genomics, proteomics, metabolomics and other molecular mechanisms to reveal the complex traits of human diseases. The significant use of omics technologies and their applications in medicine gear up the study of the pathogenesis of several disorders. The detection of biomarkers in the early onset of diseases is challenging; still, omics can discover novel molecular mechanisms and biomarkers. In this review, the different types of omics and their technologies are explicated and aimed to provide their emerging applications in cardiovascular precision medicine. These technologies significantly impact optimizing medical treatment for individuals to reach a higher level in precision medicine.

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来源期刊

Personalized medicine 医学-药学

CiteScore

3.30

自引率

4.30%

发文量

审稿时长

6-12 weeks

期刊介绍： Personalized Medicine (ISSN 1741-0541) translates recent genomic, genetic and proteomic advances into the clinical context. The journal provides an integrated forum for all players involved - academic and clinical researchers, pharmaceutical companies, regulatory authorities, healthcare management organizations, patient organizations and others in the healthcare community. Personalized Medicine assists these parties to shape thefuture of medicine by providing a platform for expert commentary and analysis. The journal addresses scientific, commercial and policy issues in the field of precision medicine and includes news and views, current awareness regarding new biomarkers, concise commentary and analysis, reports from the conference circuit and full review articles.