伴有骨髓转移的嗜中性粒细胞-肌中性粒细胞相关神经母细胞瘤:最佳治疗方案是什么?

IF 1.8

Oncology (Williston Park, N.Y.) Pub Date : 2021-10-22 DOI:10.46883/ONC.2021.3510.0665

Mane Gizhlaryan, Tigran Aghabekyan, Tatev Arakelyan, Meri Petrosyan, Samvel Iskanyan, Gevorg Tamamyan, Lilit Sargsyan, Ruzanna Papyan

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引用次数: 1

摘要

一名19岁的女孩因舞蹈眼动、共济失调和行为障碍被送到医院。MRI示腹膜后肿瘤(横断面尺寸:3.9 x 2.5 cm，颅侧尺寸:4.6 cm)，从T12椎体延伸至L3椎体(图)，怀疑为神经母细胞瘤。然后行病变组织及骨髓活检。肿瘤及骨髓的初步病理评价(CD56+、PHOX2B+、NKX2-、Ki67 50%-55%、NSE+、CD99-)证实为低分化、高危神经母细胞瘤。

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Opsoclonus-Myoclonus-Associated Neuroblastoma With Bone Marrow Metastases: What Would Be the Best Treatment Option?

A 1.9-year-old girl was presented to the hospital with dancing eye movements, ataxia, and behavioral disorders. The MRI showed a retroperitoneal tumor (transversal size: 3.9 x 2.5 cm, craniocaudal size: 4.6 cm) extending from T12 to L3 vertebral bodies (Figure), which was suspicious for neuroblastoma. Afterwards, biopsy of the lesion and bone marrow was performed. The initial pathological evaluation (CD56+, PHOX2B+, NKX2-, Ki67 50%-55%, NSE+, CD99-) of the tumor and bone marrow confirmed the diagnosis of poorly differentiated, high-risk neuroblastoma.

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Oncology (Williston Park, N.Y.)

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