喀麦隆霍乱感染的离散时间风险结构模型。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Eric Che, Abdul-Aziz Yakubu
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引用次数: 2

摘要

在最近的一篇论文中,Che等[5]使用具有风险结构的连续时间常微分方程(ODE)模型研究了喀麦隆的霍乱感染。然而,喀麦隆的人口和报告的霍乱病例在每年的离散时间间隔进行审查。与文献[5]不同的是,本文引入了一个离散时间风险结构的霍乱模型,没有空间结构。我们使用离散时间人口方程来“拟合”喀麦隆的年人口。此外,我们使用我们的拟合离散时间模型来捕获1987年至2004年每年报告的霍乱病例,并研究2004年至2019年接种疫苗、治疗和改善卫生条件对霍乱感染人数的影响。我们的离散时间霍乱模型证实了[5]中ODE模型的结果。然而,我们的离散时间模型预测,与ODE模型的干预期(2004-2022)相比,在较短的霍乱干预期(2004-2019),霍乱病例数会减少。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A discrete-time risk-structured model of cholera infections in Cameroon.

In a recent paper, Che et al. [5] used a continuous-time Ordinary Differential Equation (ODE) model with risk structure to study cholera infections in Cameroon. However, the population and the reported cholera cases in Cameroon are censored at discrete-time annual intervals. In this paper, unlike in [5], we introduce a discrete-time risk-structured cholera model with no spatial structure. We use our discrete-time demographic equation to 'fit' the annual population of Cameroon. Furthermore, we use our fitted discrete-time model to capture the annually reported cholera cases from 1987 to 2004 and to study the impact of vaccination, treatment and improved sanitation on the number of cholera infections from 2004 to 2019. Our discrete-time cholera model confirms the results of the ODE model in [5]. However, our discrete-time model predicts a decrease in the number of cholera cases in a shorter period of cholera intervention (2004-2019) as compared to the ODE model's period of intervention (2004-2022).

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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