罕见的胰腺假乳头状肿瘤:10年的经验。

Surgery Research and Practice Pub Date : 2021-09-17 eCollection Date: 2021-01-01 DOI:10.1155/2021/7377991
Suvendu Sekhar Jena, Samrat Ray, Sri Aurobindo Prasad Das, Naimish N Mehta, Amitabh Yadav, Samiran Nundy
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引用次数: 5

摘要

实体假乳头状上皮肿瘤(SPN)是一种罕见的胰腺肿瘤,发病率为所有胰腺肿瘤的2-3%。最近发病率的增加是由于越来越多地使用影像学技术来诊断非特异性腹部疾病。我们报告在过去的十年中我们在这个肿瘤的管理机构的经验。方法:回顾性分析2011年1月至2020年12月期间因SPN手术的患者的前瞻性数据库。所有患者随访至今。结果:479例不同类型胰腺肿瘤患者中,15例(3.1%)发生SPN。平均发病年龄28岁,女性居多(12/15,80%)。最常见的位置是胰腺体和尾部(66%),平均大小为6.4 cm (2-15 cm)。在20%的病例中,肿瘤范围被定义为“边缘性可切除”。11例行远端胰腺切除术,3例保脾。R0、R1和R2分别切除12例、2例和1例患者。手术死亡率为6.7%。所有病人的随访情况都很好。结论:SPN是一种低级别恶性肿瘤,多发于女性。临床表现无特异性,影像学检查仅有助于肿瘤定位,最终诊断取决于病理。手术是治疗的主要方式,预后良好。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Rare Pseudopapillary Neoplasm of the Pancreas: A 10-Year Experience.

Rare Pseudopapillary Neoplasm of the Pancreas: A 10-Year Experience.

Rare Pseudopapillary Neoplasm of the Pancreas: A 10-Year Experience.

Rare Pseudopapillary Neoplasm of the Pancreas: A 10-Year Experience.

Introduction: The solid pseudopapillary epithelial neoplasm (SPN) is a rare form of pancreatic neoplasm with an incidence of 2-3% of all pancreatic tumours. The recent increase in incidence is attributed to the increasing use of imaging techniques for nonspecific abdominal complaints. We report our institutional experience in the management of this tumour over the last decade.

Method: We retrospectively analyzed from a prospectively maintained database of patients from January 2011 to December 2020 who were operated upon for SPN. All the patients were followed till date.

Results: Of 479 patients operated on for various types of pancreatic tumours during this period, 15 (3.1%) had SPN. The mean age of presentation was 28 years with a female preponderance (12/15, 80%). The most common location was the body and tail of the pancreas (66%), and the mean size was 6.4 cm (2-15 cm). The tumour extent was defined as 'borderline resectable' in 20% of cases. Distal pancreatectomy was done in 11 patients with spleen preservation in 3. R0, R1, and R2 resection were done in 12, 2, and 1 patient(s), respectively. The operative mortality was 6.7%. All the patients are doing well on follow-up.

Conclusion: SPN is a low-grade malignant tumour with a strong female predilection. Clinical manifestations have no specificity, imaging examination only contributes tumour location, and the final diagnosis rests on pathology. Surgery is the main modality of treatment and carries a good prognosis.

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期刊介绍: Surgery Research and Practice is a peer-reviewed, Open Access journal that provides a forum for surgeons and the surgical research community. The journal publishes original research articles, review articles, and clinical studies focusing on clinical and laboratory research relevant to surgical practice and teaching, with an emphasis on findings directly affecting surgical management.
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