Filomena Fortinguerra, Valeria Belleudi, Francesca Romana Poggi, Renata Bortolus, Aurora Puccini, Valentina Solfrini, Paolo Stella, Francesco Trotta
{"title":"意大利孕前、孕期和产后的药物处方:一项基于人群的研究。","authors":"Filomena Fortinguerra, Valeria Belleudi, Francesca Romana Poggi, Renata Bortolus, Aurora Puccini, Valentina Solfrini, Paolo Stella, Francesco Trotta","doi":"10.4415/ANN_21_03_09","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Monitoring medicine prescriptions in pregnancy is an aspect of extreme interest in term of public health.</p><p><strong>Methods: </strong>A retrospective prevalence study using administrative healthcare databases was performed in order to evaluate medication prescriptions in Italy. A cohort of 274,938 pregnant women (15-49 years) residing in three Italian regions (Emilia-Romagna, Lazio, Puglia), who delivered in 2014-2017, were enrolled. The prevalence of medication use was estimated as the proportion of pregnant women with any medication prescription in each of the following five trimesters: 1 before pregnancy (pre-T), 3 during pregnancy (1st TP, 2nd TP, 3rd TP) and 1 after pregnancy (post-T).</p><p><strong>Results: </strong>About 80% of enrolled pregnant women received at least one prescription during pregnancy, 36.5% before pregnancy and 50.7% in the post-partum. The most prescribed medicine was folic acid (42%), mostly used in 1st TP (35%). Progesterone use was concentrated in 1st TP (19%) and increased as the number of previous abortions. Pregnancy use of antidiabetics, antihypertensives, and thyroid preparations were 24.1‰, 21.5‰, 101.8‰, respectively.</p><p><strong>Conclusions: </strong>At the national level, this study confirmed the prescriptive trend observed in other European studies, but a regional variability for all medication groups was found. Further studies are needed in order to identify determinants of medication prescriptions during pregnancy in Italy.</p>","PeriodicalId":8246,"journal":{"name":"Annali dell'Istituto superiore di sanita","volume":"57 3","pages":"249-258"},"PeriodicalIF":1.1000,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Medication prescriptions before, during and after pregnancy in Italy: a population-based study.\",\"authors\":\"Filomena Fortinguerra, Valeria Belleudi, Francesca Romana Poggi, Renata Bortolus, Aurora Puccini, Valentina Solfrini, Paolo Stella, Francesco Trotta\",\"doi\":\"10.4415/ANN_21_03_09\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Monitoring medicine prescriptions in pregnancy is an aspect of extreme interest in term of public health.</p><p><strong>Methods: </strong>A retrospective prevalence study using administrative healthcare databases was performed in order to evaluate medication prescriptions in Italy. A cohort of 274,938 pregnant women (15-49 years) residing in three Italian regions (Emilia-Romagna, Lazio, Puglia), who delivered in 2014-2017, were enrolled. The prevalence of medication use was estimated as the proportion of pregnant women with any medication prescription in each of the following five trimesters: 1 before pregnancy (pre-T), 3 during pregnancy (1st TP, 2nd TP, 3rd TP) and 1 after pregnancy (post-T).</p><p><strong>Results: </strong>About 80% of enrolled pregnant women received at least one prescription during pregnancy, 36.5% before pregnancy and 50.7% in the post-partum. The most prescribed medicine was folic acid (42%), mostly used in 1st TP (35%). Progesterone use was concentrated in 1st TP (19%) and increased as the number of previous abortions. Pregnancy use of antidiabetics, antihypertensives, and thyroid preparations were 24.1‰, 21.5‰, 101.8‰, respectively.</p><p><strong>Conclusions: </strong>At the national level, this study confirmed the prescriptive trend observed in other European studies, but a regional variability for all medication groups was found. 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Medication prescriptions before, during and after pregnancy in Italy: a population-based study.
Background: Monitoring medicine prescriptions in pregnancy is an aspect of extreme interest in term of public health.
Methods: A retrospective prevalence study using administrative healthcare databases was performed in order to evaluate medication prescriptions in Italy. A cohort of 274,938 pregnant women (15-49 years) residing in three Italian regions (Emilia-Romagna, Lazio, Puglia), who delivered in 2014-2017, were enrolled. The prevalence of medication use was estimated as the proportion of pregnant women with any medication prescription in each of the following five trimesters: 1 before pregnancy (pre-T), 3 during pregnancy (1st TP, 2nd TP, 3rd TP) and 1 after pregnancy (post-T).
Results: About 80% of enrolled pregnant women received at least one prescription during pregnancy, 36.5% before pregnancy and 50.7% in the post-partum. The most prescribed medicine was folic acid (42%), mostly used in 1st TP (35%). Progesterone use was concentrated in 1st TP (19%) and increased as the number of previous abortions. Pregnancy use of antidiabetics, antihypertensives, and thyroid preparations were 24.1‰, 21.5‰, 101.8‰, respectively.
Conclusions: At the national level, this study confirmed the prescriptive trend observed in other European studies, but a regional variability for all medication groups was found. Further studies are needed in order to identify determinants of medication prescriptions during pregnancy in Italy.
期刊介绍：
Annali dell’Istituto Superiore di Sanità is a peer reviewed quarterly science journal which publishes research articles in biomedicine, translational research and in many other disciplines of the health sciences. The journal includes the following material: original articles, reviews, commentaries, editorials, brief and technical notes, book reviews.
The publication of Monographic Sections has been discontinued. In case you wish to present a small number of coordinated contributions on specific themes concerning priorities in public health, please contact the Editorial office.
The journal is in English.
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