{"title":"碱性饮用水对绝经后骨质疏松症妇女骨密度的影响","authors":"Sanaz Fasihi, Siavash Fazelian, Farinaz Farahbod, Fateme Moradi, Morteza Dehghan","doi":"10.6118/jmm.20036","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>Postmenopausal women are predisposed to osteoporosis, and those on acidic diets are at a higher risk, because it has been demonstrated that such diets have adverse effects on bone health. In this study, the effect of alkaline drinking water on bone mineral density was evaluated in postmenopausal women with osteoporosis.</p><p><strong>Methods: </strong>One hundred postmenopausal women with osteoporosis (T-score ≤ -2.5) were equally divided into an intervention group and a control group (n = 50 each). The intervention group received calcium D (daily), alkaline drinking water (1.5 L daily with pH 8.6 ± 0.3), and Osteofos tablet (70 mg weekly), whereas the control group received only calcium D and Osteofos tablet for 3 months. T-scores of the femur and spine bones were obtained using bone densitometry before and 3 months after the intervention.</p><p><strong>Results: </strong>After the intervention, the mean T-scores of the femur and spine bones significantly increased in both the control and intervention groups (<i>P</i> < 0.05). However, the mean changes in the spine T-score were significantly higher in the intervention group (0.39 ± 0.07) than in the control group (0.08 ± 0.01) (<i>P</i> < 0.05). No significant differences were observed in the mean changes in the femur T-score between the two groups.</p><p><strong>Conclusion: </strong>Our findings demonstrate that drinking alkaline water improves spine T-scores in postmenopausal women with osteoporosis. Hence, alkaline water can be used to treat osteoporosis due to increased bone density in postmenopausal women. Long-term interventions are necessary to confirm the effects of alkaline water on femur density.</p>","PeriodicalId":16410,"journal":{"name":"Journal of Menopausal Medicine","volume":"27 2","pages":"94-101"},"PeriodicalIF":0.0000,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ee/06/jmm-27-94.PMC8408322.pdf","citationCount":"0","resultStr":"{\"title\":\"Effect of Alkaline Drinking Water on Bone Density of Postmenopausal Women with Osteoporosis.\",\"authors\":\"Sanaz Fasihi, Siavash Fazelian, Farinaz Farahbod, Fateme Moradi, Morteza Dehghan\",\"doi\":\"10.6118/jmm.20036\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objectives: </strong>Postmenopausal women are predisposed to osteoporosis, and those on acidic diets are at a higher risk, because it has been demonstrated that such diets have adverse effects on bone health. In this study, the effect of alkaline drinking water on bone mineral density was evaluated in postmenopausal women with osteoporosis.</p><p><strong>Methods: </strong>One hundred postmenopausal women with osteoporosis (T-score ≤ -2.5) were equally divided into an intervention group and a control group (n = 50 each). The intervention group received calcium D (daily), alkaline drinking water (1.5 L daily with pH 8.6 ± 0.3), and Osteofos tablet (70 mg weekly), whereas the control group received only calcium D and Osteofos tablet for 3 months. T-scores of the femur and spine bones were obtained using bone densitometry before and 3 months after the intervention.</p><p><strong>Results: </strong>After the intervention, the mean T-scores of the femur and spine bones significantly increased in both the control and intervention groups (<i>P</i> < 0.05). However, the mean changes in the spine T-score were significantly higher in the intervention group (0.39 ± 0.07) than in the control group (0.08 ± 0.01) (<i>P</i> < 0.05). No significant differences were observed in the mean changes in the femur T-score between the two groups.</p><p><strong>Conclusion: </strong>Our findings demonstrate that drinking alkaline water improves spine T-scores in postmenopausal women with osteoporosis. Hence, alkaline water can be used to treat osteoporosis due to increased bone density in postmenopausal women. Long-term interventions are necessary to confirm the effects of alkaline water on femur density.</p>\",\"PeriodicalId\":16410,\"journal\":{\"name\":\"Journal of Menopausal Medicine\",\"volume\":\"27 2\",\"pages\":\"94-101\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ee/06/jmm-27-94.PMC8408322.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Menopausal Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.6118/jmm.20036\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Menopausal Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.6118/jmm.20036","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
目的:绝经后妇女易患骨质疏松症,而酸性饮食的妇女患骨质疏松症的风险更高,因为事实证明,酸性饮食对骨骼健康有不利影响。本研究评估了碱性饮用水对绝经后骨质疏松症妇女骨矿物质密度的影响:方法:将 100 名绝经后骨质疏松症妇女(T 值≤-2.5)平均分为干预组和对照组(各 50 人)。干预组每天服用钙 D、碱性饮用水(每天 1.5 升,pH 值为 8.6 ± 0.3)和 Osteofos 片剂(每周 70 毫克),而对照组只服用钙 D 和 Osteofos 片剂,为期 3 个月。干预前和干预后 3 个月,采用骨密度测量法测量股骨和脊柱骨的 T 值:干预后,对照组和干预组的股骨和脊柱骨的平均 T 值均明显增加(P < 0.05)。然而,干预组脊柱T值的平均变化(0.39 ± 0.07)明显高于对照组(0.08 ± 0.01)(P < 0.05)。两组间股骨 T 值的平均变化无明显差异:我们的研究结果表明,饮用碱性水可改善绝经后骨质疏松症妇女的脊柱 T 值。因此,碱性水可用于治疗绝经后妇女因骨密度增加而导致的骨质疏松症。要确认碱性水对股骨密度的影响,必须进行长期干预。
Effect of Alkaline Drinking Water on Bone Density of Postmenopausal Women with Osteoporosis.
Objectives: Postmenopausal women are predisposed to osteoporosis, and those on acidic diets are at a higher risk, because it has been demonstrated that such diets have adverse effects on bone health. In this study, the effect of alkaline drinking water on bone mineral density was evaluated in postmenopausal women with osteoporosis.
Methods: One hundred postmenopausal women with osteoporosis (T-score ≤ -2.5) were equally divided into an intervention group and a control group (n = 50 each). The intervention group received calcium D (daily), alkaline drinking water (1.5 L daily with pH 8.6 ± 0.3), and Osteofos tablet (70 mg weekly), whereas the control group received only calcium D and Osteofos tablet for 3 months. T-scores of the femur and spine bones were obtained using bone densitometry before and 3 months after the intervention.
Results: After the intervention, the mean T-scores of the femur and spine bones significantly increased in both the control and intervention groups (P < 0.05). However, the mean changes in the spine T-score were significantly higher in the intervention group (0.39 ± 0.07) than in the control group (0.08 ± 0.01) (P < 0.05). No significant differences were observed in the mean changes in the femur T-score between the two groups.
Conclusion: Our findings demonstrate that drinking alkaline water improves spine T-scores in postmenopausal women with osteoporosis. Hence, alkaline water can be used to treat osteoporosis due to increased bone density in postmenopausal women. Long-term interventions are necessary to confirm the effects of alkaline water on femur density.