Ahmed Halfadji, Mohamed Naous, Farida Bettiche, Abdelkrim Touabet
{"title":"阿尔及利亚西北部污染土壤中16种优先多环芳烃的人体健康评价","authors":"Ahmed Halfadji, Mohamed Naous, Farida Bettiche, Abdelkrim Touabet","doi":"10.5696/2156-9614-11.31.210914","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental organic contaminants generated by incomplete combustion of organic materials that are widely distributed in soils.</p><p><strong>Objectives: </strong>This study represents the first attempt to examine the health toxicity of 16 detected PAHs in contaminated soil, via different exposure pathways to populations in northwestern Algeria.</p><p><strong>Methods: </strong>The toxicity equivalency quotients (TEQ) of PAHs were evaluated. The carcinogenic risk assessment of incremental lifetime cancer risk (ILCR) from ingestion, inhalation, and dermal exposure pathways to each PAH in soil are described.</p><p><strong>Results: </strong>Incremental lifetime cancer risk values were in the upper limit of the tolerable range (10<sup>-6</sup>-10<sup>-4</sup>) for adults and children. The total cancer risk of PAH-contaminated soils for children, adolescents and adults was 2.48×10<sup>-5</sup>, 2.04×10<sup>-5</sup> and 3.12×10<sup>-5</sup>mg.kg<sup>-1</sup>d<sup>-1</sup>, respectively. The highest potential cancer risks were identified for adults and children, with adolescents having the lowest risks. Across exposure pathways, the dermal contact and ingestion pathways had the greatest contributions to the carcinogenic risk of human exposure to PAHs.</p><p><strong>Conclusions: </strong>Further research and guidelines are needed for risk assessments of PAHs in agricultural, residential/urban, and industrial areas, and further risk assessments should include risks posed by exposure through air.</p><p><strong>Competing interests: </strong>The authors declare no competing financial interests.</p>","PeriodicalId":52138,"journal":{"name":"Journal of Health and Pollution","volume":" ","pages":"210914"},"PeriodicalIF":2.4000,"publicationDate":"2021-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383786/pdf/","citationCount":"6","resultStr":"{\"title\":\"Human Health Assessment of Sixteen Priority Polycyclic Aromatic Hydrocarbons in Contaminated Soils of Northwestern Algeria.\",\"authors\":\"Ahmed Halfadji, Mohamed Naous, Farida Bettiche, Abdelkrim Touabet\",\"doi\":\"10.5696/2156-9614-11.31.210914\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental organic contaminants generated by incomplete combustion of organic materials that are widely distributed in soils.</p><p><strong>Objectives: </strong>This study represents the first attempt to examine the health toxicity of 16 detected PAHs in contaminated soil, via different exposure pathways to populations in northwestern Algeria.</p><p><strong>Methods: </strong>The toxicity equivalency quotients (TEQ) of PAHs were evaluated. The carcinogenic risk assessment of incremental lifetime cancer risk (ILCR) from ingestion, inhalation, and dermal exposure pathways to each PAH in soil are described.</p><p><strong>Results: </strong>Incremental lifetime cancer risk values were in the upper limit of the tolerable range (10<sup>-6</sup>-10<sup>-4</sup>) for adults and children. The total cancer risk of PAH-contaminated soils for children, adolescents and adults was 2.48×10<sup>-5</sup>, 2.04×10<sup>-5</sup> and 3.12×10<sup>-5</sup>mg.kg<sup>-1</sup>d<sup>-1</sup>, respectively. The highest potential cancer risks were identified for adults and children, with adolescents having the lowest risks. Across exposure pathways, the dermal contact and ingestion pathways had the greatest contributions to the carcinogenic risk of human exposure to PAHs.</p><p><strong>Conclusions: </strong>Further research and guidelines are needed for risk assessments of PAHs in agricultural, residential/urban, and industrial areas, and further risk assessments should include risks posed by exposure through air.</p><p><strong>Competing interests: </strong>The authors declare no competing financial interests.</p>\",\"PeriodicalId\":52138,\"journal\":{\"name\":\"Journal of Health and Pollution\",\"volume\":\" \",\"pages\":\"210914\"},\"PeriodicalIF\":2.4000,\"publicationDate\":\"2021-08-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383786/pdf/\",\"citationCount\":\"6\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Health and Pollution\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5696/2156-9614-11.31.210914\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2021/9/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q1\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Health and Pollution","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5696/2156-9614-11.31.210914","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2021/9/1 0:00:00","PubModel":"eCollection","JCR":"Q1","JCRName":"Medicine","Score":null,"Total":0}
Human Health Assessment of Sixteen Priority Polycyclic Aromatic Hydrocarbons in Contaminated Soils of Northwestern Algeria.
Background: Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental organic contaminants generated by incomplete combustion of organic materials that are widely distributed in soils.
Objectives: This study represents the first attempt to examine the health toxicity of 16 detected PAHs in contaminated soil, via different exposure pathways to populations in northwestern Algeria.
Methods: The toxicity equivalency quotients (TEQ) of PAHs were evaluated. The carcinogenic risk assessment of incremental lifetime cancer risk (ILCR) from ingestion, inhalation, and dermal exposure pathways to each PAH in soil are described.
Results: Incremental lifetime cancer risk values were in the upper limit of the tolerable range (10-6-10-4) for adults and children. The total cancer risk of PAH-contaminated soils for children, adolescents and adults was 2.48×10-5, 2.04×10-5 and 3.12×10-5mg.kg-1d-1, respectively. The highest potential cancer risks were identified for adults and children, with adolescents having the lowest risks. Across exposure pathways, the dermal contact and ingestion pathways had the greatest contributions to the carcinogenic risk of human exposure to PAHs.
Conclusions: Further research and guidelines are needed for risk assessments of PAHs in agricultural, residential/urban, and industrial areas, and further risk assessments should include risks posed by exposure through air.
Competing interests: The authors declare no competing financial interests.
期刊介绍：
The Journal of Health and Pollution (JH&P) was initiated with funding from the European Union and World Bank and continues to be a Platinum Open Access Journal. There are no publication or viewing charges. That is, there are no charges to readers or authors. Upon peer-review and acceptance, all articles are made available online. The high-ranking editorial board is comprised of active members who participate in JH&P submissions and editorial policies. The Journal of Health and Pollution welcomes manuscripts based on original research as well as findings from re-interpretation and examination of existing data. JH&P focuses on point source pollution, related health impacts, environmental control and remediation technology. JH&P also has an interest in ambient and indoor pollution. Pollutants of particular interest include heavy metals, pesticides, radionuclides, dioxins, polychlorinated biphenyls (PCBs), polycyclic aromatic hydrocarbons (PAHs), volatile organic compounds (VOCs), air particulates (PM10 and PM2.5), and other severe and persistent toxins. JH&P emphasizes work relating directly to low and middle-income countries, however relevant work relating to high-income countries will be considered on a case-by-case basis.
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