Stijn van Cruchten, Eefke C Warmerdam, Dagmar R J Kempink, Victor A de Ridder
{"title":"2-10岁儿童闭合性股骨干骨折的治疗:系统回顾和荟萃分析。","authors":"Stijn van Cruchten, Eefke C Warmerdam, Dagmar R J Kempink, Victor A de Ridder","doi":"10.1007/s00068-021-01752-7","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To review current literature on treatment of closed femoral shaft fractures in children of 2-10 years old, with subgroup analysis of children aged 2-6 years, comparing intramedullary nailing (IMN) to conservative treatment modalities.</p><p><strong>Methods: </strong>We included clinical trials and observational studies that compared traction and subsequent casting (TSC), spica casting and IMN for treatment of femur shaft fractures in children of 2-10 years of age. Subgroup analysis of children aged 2-6 years was performed.</p><p><strong>Results: </strong>Compared to treatment with immediate spica casting, IMN led to significantly less coronal angulation (mean difference (MD): 2.03 degrees, confidence interval (CI) 1.15-2.90), less sagittal angulation (MD: 1.59 degrees, CI 0.82-2.35) and lower rates of LLD (Risk difference (RD): 0.07, CI 0.03-0.11). In terms of rehabilitation, IMN leaded to shorter time until walking with aids (MD: 31.53 days, CI 16.02-47.03), shorter time until independent ambulation (MD: 26.59 days, CI 22.07, 31.11) and shorter time until full weight bearing (MD: 27.05 days, CI 6.11, 47,99). Compared to TSC, IMN led to a lower rate of malunion (RD: 0.31, CI 0.05-0.56), shorter hospital stays (MD: 12.48 days, CI 11.57, 13.39), time until walking with aids (MD: 54.55, CI 40.05-69.04) and full weight bearing (MD: 27.05 days [6.11, 47,99]).</p><p><strong>Conclusion: </strong>Although a lack of quality evidence, this systematic review showed a clear tendency to treatment with elastic intramedullary nails of femoral shaft fractures in children of 2-10 years of age.</p><p><strong>Level of evidence: 3: </strong></p>","PeriodicalId":520620,"journal":{"name":"European journal of trauma and emergency surgery : official publication of the European Trauma Society","volume":" ","pages":"3409-3427"},"PeriodicalIF":0.0000,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s00068-021-01752-7","citationCount":"12","resultStr":"{\"title\":\"Treatment of closed femoral shaft fractures in children aged 2-10 years: a systematic review and meta-analysis.\",\"authors\":\"Stijn van Cruchten, Eefke C Warmerdam, Dagmar R J Kempink, Victor A de Ridder\",\"doi\":\"10.1007/s00068-021-01752-7\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To review current literature on treatment of closed femoral shaft fractures in children of 2-10 years old, with subgroup analysis of children aged 2-6 years, comparing intramedullary nailing (IMN) to conservative treatment modalities.</p><p><strong>Methods: </strong>We included clinical trials and observational studies that compared traction and subsequent casting (TSC), spica casting and IMN for treatment of femur shaft fractures in children of 2-10 years of age. Subgroup analysis of children aged 2-6 years was performed.</p><p><strong>Results: </strong>Compared to treatment with immediate spica casting, IMN led to significantly less coronal angulation (mean difference (MD): 2.03 degrees, confidence interval (CI) 1.15-2.90), less sagittal angulation (MD: 1.59 degrees, CI 0.82-2.35) and lower rates of LLD (Risk difference (RD): 0.07, CI 0.03-0.11). In terms of rehabilitation, IMN leaded to shorter time until walking with aids (MD: 31.53 days, CI 16.02-47.03), shorter time until independent ambulation (MD: 26.59 days, CI 22.07, 31.11) and shorter time until full weight bearing (MD: 27.05 days, CI 6.11, 47,99). Compared to TSC, IMN led to a lower rate of malunion (RD: 0.31, CI 0.05-0.56), shorter hospital stays (MD: 12.48 days, CI 11.57, 13.39), time until walking with aids (MD: 54.55, CI 40.05-69.04) and full weight bearing (MD: 27.05 days [6.11, 47,99]).</p><p><strong>Conclusion: </strong>Although a lack of quality evidence, this systematic review showed a clear tendency to treatment with elastic intramedullary nails of femoral shaft fractures in children of 2-10 years of age.</p><p><strong>Level of evidence: 3: </strong></p>\",\"PeriodicalId\":520620,\"journal\":{\"name\":\"European journal of trauma and emergency surgery : official publication of the European Trauma Society\",\"volume\":\" \",\"pages\":\"3409-3427\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1007/s00068-021-01752-7\",\"citationCount\":\"12\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"European journal of trauma and emergency surgery : official publication of the European Trauma Society\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s00068-021-01752-7\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2021/8/2 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"European journal of trauma and emergency surgery : official publication of the European Trauma Society","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00068-021-01752-7","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2021/8/2 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 12
摘要
目的:回顾目前关于2-10岁儿童闭合性股骨干骨折治疗的文献,并对2-6岁儿童进行亚组分析,比较髓内钉(IMN)与保守治疗方式。方法:我们纳入了临床试验和观察性研究,比较牵引和后续铸造(TSC)、spica铸造和IMN治疗2-10岁儿童股骨骨干骨折的效果。对2 ~ 6岁儿童进行亚组分析。结果:与即刻spica铸造治疗相比,IMN显著减少冠状面成角(平均差值(MD): 2.03度,可信区间(CI) 1.15-2.90),减少矢状面成角(MD: 1.59度,CI 0.82-2.35),降低LLD发生率(风险差值(RD): 0.07, CI 0.03-0.11)。在康复方面,IMN可缩短患者到辅助行走所需时间(MD: 31.53 d, CI 16.02-47.03),缩短患者到独立行走所需时间(MD: 26.59 d, CI 22.07, 31.11),缩短患者到完全负重所需时间(MD: 27.05 d, CI 6.11, 47,99)。与TSC相比,IMN导致较低的不愈合率(RD: 0.31, CI 0.05-0.56),较短的住院时间(MD: 12.48天,CI 11.57, 13.39),到辅助行走的时间(MD: 54.55, CI 40.05-69.04)和完全负重(MD: 27.05天[6.11,47,99])。结论:虽然缺乏高质量的证据,但本系统综述显示弹性髓内钉治疗2-10岁儿童股骨干骨折有明显的趋势。证据等级:3;
Treatment of closed femoral shaft fractures in children aged 2-10 years: a systematic review and meta-analysis.
Objective: To review current literature on treatment of closed femoral shaft fractures in children of 2-10 years old, with subgroup analysis of children aged 2-6 years, comparing intramedullary nailing (IMN) to conservative treatment modalities.
Methods: We included clinical trials and observational studies that compared traction and subsequent casting (TSC), spica casting and IMN for treatment of femur shaft fractures in children of 2-10 years of age. Subgroup analysis of children aged 2-6 years was performed.
Results: Compared to treatment with immediate spica casting, IMN led to significantly less coronal angulation (mean difference (MD): 2.03 degrees, confidence interval (CI) 1.15-2.90), less sagittal angulation (MD: 1.59 degrees, CI 0.82-2.35) and lower rates of LLD (Risk difference (RD): 0.07, CI 0.03-0.11). In terms of rehabilitation, IMN leaded to shorter time until walking with aids (MD: 31.53 days, CI 16.02-47.03), shorter time until independent ambulation (MD: 26.59 days, CI 22.07, 31.11) and shorter time until full weight bearing (MD: 27.05 days, CI 6.11, 47,99). Compared to TSC, IMN led to a lower rate of malunion (RD: 0.31, CI 0.05-0.56), shorter hospital stays (MD: 12.48 days, CI 11.57, 13.39), time until walking with aids (MD: 54.55, CI 40.05-69.04) and full weight bearing (MD: 27.05 days [6.11, 47,99]).
Conclusion: Although a lack of quality evidence, this systematic review showed a clear tendency to treatment with elastic intramedullary nails of femoral shaft fractures in children of 2-10 years of age.