大麻使用对退伍军人PTSD治疗结果的影响。

The Mental Health Clinician Pub Date : 2021-07-16 eCollection Date: 2021-07-01 DOI:10.9740/mhc.2021.07.238
Meagan Petersen, Katherine Koller, Craig Straley, Ellen Reed
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引用次数: 1

摘要

导读:研究人员发现anandamide(一种内源性大麻素)和大麻素1型受体的激活促进了厌恶记忆的消除。一些理论认为大麻素(如大麻中的大麻素)可能为创伤后应激障碍提供一种新的治疗方法,而另一些人则认为它可能会加重症状。当前研究的目的是确定大麻的使用是否会影响退伍军人PTSD的循证强化门诊治疗的成功。方法:获取2008年10月1日至2016年10月1日在巴特克里克退伍军人事务医疗中心门诊PTSD临床小组诊所就诊的退伍军人名单,随机抽取。研究参与者是年龄在18到85岁之间的退伍军人,至少有2个创伤后应激障碍检查表得分,并被诊断为创伤后应激障碍。收集的数据包括心理健康药物,使用的循证心理治疗的类型和数量,以及同时发生的行为健康诊断的存在。将大麻使用组与不使用大麻组进行比较,并评估与治疗成功和失败的相对数量有关的变量的差异的统计学和临床意义。结果:以白人(87.1%)和男性(95%)居多。吸食大麻组和不吸食大麻组的成功率相似(分别为51.9%和51.4%)。讨论:目前的研究并没有显示以白人男性退伍军人为主的诊断为PTSD的样本在基于大麻使用的PTSD强化治疗的成功或失败方面存在差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Effect of cannabis use on PTSD treatment outcomes in veterans.

Effect of cannabis use on PTSD treatment outcomes in veterans.

Introduction: Researchers have found anandamide (an endocannabinoid) and cannabinoid type 1 receptor activation encourages extinction of aversive memories. Some theorize cannabinoids such as those in cannabis may provide a new treatment approach for PTSD, while others suggest it may worsen symptomology. The objective of the current study was to determine if cannabis use impacts the success of evidence-based intensive outpatient PTSD treatment in a veteran population.

Methods: A list of veterans enrolled in the Battle Creek Veterans' Affairs Medical Center outpatient PTSD Clinical Team Clinic between October 1st, 2008 and October 1st, 2016 was obtained, and a random sample was identified. Study participants were veterans aged 18 to 85 years, with at least 2 PTSD Checklist scores, and a diagnosis of PTSD. Data collected included mental health medications, type and number of evidence-based psychotherapy used, and presence of co-occurring behavioral health diagnoses. The cannabis use group was compared to the no-cannabis-use group, and differences in variables pertaining to the relative number of treatment successes and failures was evaluated for statistical and clinical significance.

Results: The majority of patients were white (87.1%) and male (95%). The success rate was similar between the cannabis and no-cannabis-use groups (51.9% and 51.4%, respectively).

Discussion: The current study did not show that a predominantly white male veteran sample diagnosed with PTSD differed in intensive PTSD treatment success or failure based on cannabis use.

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