[锶成骨机制研究进展]。

Q3 Medicine

华西口腔医学杂志 Pub Date : 2020-12-01 DOI:10.7518/hxkq.2020.06.016

Ning-Ying Zhong, Li-Ping Wang

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引用次数: 2

摘要

锶(Sr)是一种广泛存在于自然界的必需微量元素。它在体内调节骨代谢中起着重要作用。Sr在元素周期表中的位置低于Fe，其化学结构和极性与Ca相似，可通过抑制破骨细胞活性和减少骨吸收，诱导骨间充质干细胞向成骨细胞分化。它通过一系列相关途径促进骨形成。锶调控骨代谢的机制近年来得到了广泛的研究。本研究旨在探讨Sr的作用机制，为其临床应用提供理论依据。

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[Research progress in the osteogenetic mechanism of strontium].

Strontium (Sr) is an essential trace element and widely exists in nature. It plays an important role in the in vivo regulation of bone metabolism. Sr locates below Fe in the periodic table, and its chemical structure and polarity are similar to those of Ca. It can induce bone mesenchymal stem cells to differentiate into osteoblasts by inhibiting the activity of osteoclasts and reducing bone resorption. It promotes bone formation through a series of related pathways. The mechanism of Sr regulation of bone metabolism has been extensively researched in recent years. The current study aims to investigate the mechanism of Sr and provide a theoretical basis for its clinical application.

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来源期刊

华西口腔医学杂志 Medicine-Medicine (all)

CiteScore

0.80

自引率

0.00%

发文量

6397

期刊介绍： West China Journal of Stomatology (WCJS, pISSN 1000-1182, eISSN 2618-0456, CN 51-1169/R), published bimonthly, is a peer-reviewed Open Access journal, hosted by Sichuan university and Ministry of Education of the People's Republic of China. WCJS was established in 1983 and indexed in Medline/Pubmed, SCOPUS, EBSCO, Chemical Abstract(CA), CNKI, WANFANG Data, etc.