重度社区获得性肺炎患者严重程度评分系统的评价。

IF 1.6 Q2 MEDICINE, GENERAL & INTERNAL
Romanian Journal of Internal Medicine Pub Date : 2021-11-20 Print Date: 2021-12-01 DOI:10.2478/rjim-2021-0025
Katerina Spasovska, Krsto Grozdanovski, Zvonko Milenkovic, Mile Bosilkovski, Marija Cvetanovska, Nikola Kuzmanovski, Kosta Kapsarov, Emilija Atanasovska
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引用次数: 1

摘要

背景。本研究的目的是评估严重性评分系统预测严重社区获得性肺炎患者30天死亡率的能力。方法。该研究纳入了北马其顿共和国斯科普里大学传染病诊所重症监护室住院的98名年龄≥18岁的社区获得性肺炎患者,为期3年。我们记录了人口统计学、临床和常见的生化参数。入院时计算5个严重程度评分:CURB 65(意识混乱、尿素、呼吸率、血压、年龄≥65岁)、SCAP(严重社区获得性肺炎评分)、SAPS II(简化急性生理评分)、SOFA(序期器官衰竭评估评分)和MPM(死亡率预测模型)。主要结局变量为30天住院死亡率。结果。患者平均年龄59.08±15.76岁,男性居多(68%)。总体30天死亡率为52%。非幸存者的Charlson合并症指数升高(3.72±2.33),并与预后相关。死亡患者的所有严重程度指标均较高,分析组间差异有统计学意义。30 d死亡率5项评分的曲线下面积(AUC)分别为0.670、0.732、0.726、0.785和0.777。结论。广泛使用的严重程度评分准确地检测出肺炎患者预后不良的风险增加,但没有一种评分单独显示出比其他评分有任何优势。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evaluation of severity scoring systems in patients with severe community acquired pneumonia.

Background. The aim of this study was to evaluate the ability of severity scoring systems to predict 30-day mortality in patients with severe community-acquired pneumonia. Methods. The study included 98 patients aged ≥18 years with community acquired pneumonia hospitalized at the Intensive Care Unit of the University Clinic for Infectious Diseases in Skopje, Republic of North Macedonia, during a 3-year period. We recorded demographic, clinical and common biochemical parameters. Five severity scores were calculated at admission: CURB 65 (Confusion, Urea, Respiratory Rate, Blood pressure, Age ≥65 years), SCAP (Severe Community Acquired Pneumonia score), SAPS II (Simplified Acute Physiology Score), SOFA (Sequential Organ Failure Assessment Score) and MPM (Mortality Prediction Model). Primary outcome variable was 30-day in-hospital mortality. Results. The mean age of the patients was 59.08 ± 15.76 years, predominantly males (68%). The overall 30-day mortality was 52%. Charlson Comorbidity index was increased in non-survivors (3.72 ± 2.33) and was associated with the outcome. All severity indexes had higher values in patients who died, that showed statistical significance between the analysed groups. The areas under curve (AUC) values of the five scores for 30-day mortality were 0.670, 0.732, 0,726, 0.785 and 0.777, respectively. Conclusion. Widely used severity scores accurately detected patients with pneumonia that had increased risk for poor outcome, but none of them individually demonstrated any advantage over the others.

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来源期刊
Romanian Journal of Internal Medicine
Romanian Journal of Internal Medicine MEDICINE, GENERAL & INTERNAL-
CiteScore
3.20
自引率
5.30%
发文量
35
审稿时长
15 weeks
期刊介绍: Romanian Journal of Physics is a journal publishing physics contributions on the following themes: •Theoretical Physics & Applied Mathematics •Nuclear Physics •Solid State Physics & Materials Science •Statistical Physics & Quantum Mechanics •Optics •Spectroscopy •Plasma & Lasers •Nuclear & Elementary Particles Physics •Atomic and Molecular Physics •Astrophysics •Atmosphere and Earth Science •Environment Protection
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