麻醉选择在改善心脏手术后预后中的作用。

Q2 Medicine

Romanian journal of anaesthesia and intensive care Pub Date : 2020-12-01 Epub Date: 2020-12-31 DOI:10.2478/rjaic-2020-0017

Mihai Stefan, Daniela Filipescu

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引用次数: 2

摘要

临床背景:在心脏手术中，挥发性麻醉剂(VAs)已被证明可以保护心肌细胞免受缺血和再灌注损伤。临床问题:多项试验和荟萃分析显示，在心脏手术中，与静脉麻醉相比，VAs与更好的结果相关。然而，最近一项大型随机对照试验的数据并没有证实在这一人群中，与全静脉麻醉相比，静脉麻醉具有优越性。综述目的:这篇小型综述介绍了VA的心脏保护作用，它们在心脏手术中的临床应用，以及比较VA与静脉麻醉在降低围手术期发病率方面的最新证据。目前，在改善心脏手术后的预后方面，静脉麻醉并没有明显优于静脉麻醉。

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Role of Anaesthetic Choice in Improving Outcome after Cardiac Surgery.

Clinical background: Volatile anaesthetics (VAs) have been shown to protect cardiomyocytes against ischaemia and reperfusion injury in cardiac surgery.

Clinical problems: VAs have been shown in multiple trials and meta-analyses to be associated with better outcomes when compared to intravenous anaesthesia in cardiac surgery. However, recent data from a large randomised controlled trial do not confirm the superiority of VA as compared to total intravenous anaesthesia in this population.

Review objectives: This mini review presents the VA cardioprotective effects, their clinical use in cardiac surgery and the most recent evidence that compares VA to intravenous anaesthesia for reducing perioperative morbidity. At present, there is no clear superiority of VA over intravenous anaesthesia in improving the outcome after cardiac surgery.

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来源期刊

Romanian journal of anaesthesia and intensive care Medicine-Emergency Medicine

CiteScore

2.30

自引率

0.00%

发文量

期刊介绍： The Romanian Journal of Anaesthesia and Intensive Care is the official journal of the Romanian Society of Anaesthesia and Intensive Care and has been published continuously since 1994. It is intended mainly for anaesthesia and intensive care providers, but it is also aimed at specialists in emergency medical care and in pain research and management. The Journal is indexed in Scopus, Embase, PubMed Central as well as the databases of the Romanian Ministry of Education and Research (CNCSIS) B+ category. The Journal publishes two issues per year, the first one in April and the second one in October, and contains original articles, reviews, case reports, letters to the editor, book reviews and commentaries. The Journal is distributed free of charge to the members of the Romanian Society of Anaesthesia and Intensive Care.