精神病临床高危青年的阴性症状和言语停顿

IF 8.3 2区材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY

ACS Applied Materials & Interfaces Pub Date : 2021-01-22 DOI:10.1038/s41537-020-00132-1

Emma R Stanislawski, Zarina R Bilgrami, Cansu Sarac, Sahil Garg, Stephen Heisig, Guillermo A Cecchi, Carla Agurto, Cheryl M Corcoran

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引用次数: 16

摘要

异常停顿是精神分裂症的特征，并与其阴性症状密切相关。在这里，我们发现停顿行为与临床精神病高风险(CHR)个体的阴性症状有关，并且与句法复杂性的测量有关-短语长度和引入从句的限定词的使用-我们之前在相同的CHR队列中显示，以帮助组成预测精神病的分类器。这些发现表明，在话语规划和言语自我监控方面存在一种常见的缺陷，这种缺陷既影响言语，也影响语言，这在阴性症状的临床评分中可以检测到。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Negative symptoms and speech pauses in youths at clinical high risk for psychosis.

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Negative symptoms and speech pauses in youths at clinical high risk for psychosis.

Aberrant pauses are characteristic of schizophrenia and are robustly associated with its negative symptoms. Here, we found that pause behavior was associated with negative symptoms in individuals at clinical high risk (CHR) for psychosis, and with measures of syntactic complexity-phrase length and usage of determiners that introduce clauses-that we previously showed in this same CHR cohort to help comprise a classifier that predicted psychosis. These findings suggest a common impairment in discourse planning and verbal self-monitoring that affects both speech and language, and which is detected in clinical ratings of negative symptoms.

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来源期刊

ACS Applied Materials & Interfaces 工程技术-材料科学：综合

CiteScore

16.00

自引率

6.30%

发文量

4978

审稿时长

1.8 months

期刊介绍： ACS Applied Materials & Interfaces is a leading interdisciplinary journal that brings together chemists, engineers, physicists, and biologists to explore the development and utilization of newly-discovered materials and interfacial processes for specific applications. Our journal has experienced remarkable growth since its establishment in 2009, both in terms of the number of articles published and the impact of the research showcased. We are proud to foster a truly global community, with the majority of published articles originating from outside the United States, reflecting the rapid growth of applied research worldwide.