肺多形性癌合并获得性血友病围手术期分流剂治疗。

IF 1.1 4区 医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS
Takashi Sakai, Yoko Azuma, Atsushi Sano, Sota Sadamoto, Naobumi Tochigi, Daisuke Nagase, Akira Iyoda
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引用次数: 0

摘要

74岁男性肺癌入院,术前血液检查显示活化部分凝血活素时间(APTT)异常。凝血因子筛选和APTT混合试验可诊断获得性血友病a (AHA)。经行旁路治疗,肺叶切除术成功,无出血并发症。术后APTT恢复正常,无需再进行AHA治疗。AHA的发病机制尚不清楚,对于需要手术的AHA患者,尚无止血策略的证据。本研究支持止血治疗的重要性,并提示恶性肿瘤可能导致AHA。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Perioperative Bypassing Agent Therapy for Pulmonary Pleomorphic Carcinoma with Acquired Hemophilia.

Perioperative Bypassing Agent Therapy for Pulmonary Pleomorphic Carcinoma with Acquired Hemophilia.

Perioperative Bypassing Agent Therapy for Pulmonary Pleomorphic Carcinoma with Acquired Hemophilia.

Perioperative Bypassing Agent Therapy for Pulmonary Pleomorphic Carcinoma with Acquired Hemophilia.

A 74-year-old man was admitted with lung cancer, and preoperative blood test showed abnormal activated partial thromboplastin time (APTT). Coagulation factor screening and APTT mixing test achieved a diagnosis of acquired hemophilia A (AHA). Bypassing agent therapy was indicated and lobectomy was successfully performed without bleeding complications. APTT returned to normal after the operation without any additional treatment for AHA. The pathogenesis of AHA is still unknown and there is no evidence for hemostatic strategy for AHA patients requiring surgery. This study supports the importance of hemostatic therapy and suggests that malignancy might cause AHA.

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来源期刊
Annals of Thoracic and Cardiovascular Surgery
Annals of Thoracic and Cardiovascular Surgery CARDIAC & CARDIOVASCULAR SYSTEMS-SURGERY
CiteScore
2.80
自引率
0.00%
发文量
56
审稿时长
4-8 weeks
期刊介绍: Information not localized
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