Victoria Psomiadou, Anastasia Prodromidou, Elpis Galati, Ioannis D Kostakis, Athanasios Maliaros, Ioannis Mamais, Nikolaos Blontzos, Fotios Lefkopoulos, Christos Iavazzo, George Vorgias
{"title":"炎症生物标志物在卵巢源性盆腔肿瘤鉴别诊断中的作用:一项单中心观察研究。","authors":"Victoria Psomiadou, Anastasia Prodromidou, Elpis Galati, Ioannis D Kostakis, Athanasios Maliaros, Ioannis Mamais, Nikolaos Blontzos, Fotios Lefkopoulos, Christos Iavazzo, George Vorgias","doi":"10.5114/wo.2021.105072","DOIUrl":null,"url":null,"abstract":"<p><strong>Aim of the study: </strong>Our aim was to analyse the feasibility of white blood cell and platelet counts along with their ratios as a prognostic factor in patients who underwent surgery for ovarian mass.</p><p><strong>Material and methods: </strong>We retrospectively studied the patients admitted in the Department of Gynaecology due to adnexal mass. The potential association of the neutrophil-to-lymphocyte-ratio (NLR), neutrophil-to-monocyte (NMR), platelet-to-lymphocyte (PLR), lymphocyte-to-monocyte (LMR), monocyte-to-platelet, and malignancy was evaluated.</p><p><strong>Results: </strong>Patients with malignant tumours were found with significantly higher ratios of NLR (<i>p</i> < 0.001) and PLR (<i>p</i> < 0.001) and lower LMR ratio (<i>p</i> < 0.001) compared to those with benign tumours. Furthermore, higher lymphocyte count (<i>p</i> = 0.04) and platelet count (<i>p</i> = 0.004) were found in cancer patients when compared with borderline tumours. No significant variations were detected regarding white blood cell count (<i>p</i> = 0.238), NMR ratio (<i>p</i> = 0.28), platelet-to-neutrophil ratio (<i>p</i> = 0.12), and platelet-to-monocyte ratio (<i>p</i> = 0.34).</p><p><strong>Conclusions: </strong>Inflammation biomarker ratios can easily and inexpensive assist in distinguishing malignant ovarian tumours from benign ones.</p>","PeriodicalId":49354,"journal":{"name":"Wspolczesna Onkologia-Contemporary Oncology","volume":null,"pages":null},"PeriodicalIF":2.9000,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f9/9f/WO-25-43726.PMC8063895.pdf","citationCount":"2","resultStr":"{\"title\":\"The role of inflammation biomarkers in differential diagnosis of pelvic tumours of ovarian origin: a single-centre observational study.\",\"authors\":\"Victoria Psomiadou, Anastasia Prodromidou, Elpis Galati, Ioannis D Kostakis, Athanasios Maliaros, Ioannis Mamais, Nikolaos Blontzos, Fotios Lefkopoulos, Christos Iavazzo, George Vorgias\",\"doi\":\"10.5114/wo.2021.105072\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Aim of the study: </strong>Our aim was to analyse the feasibility of white blood cell and platelet counts along with their ratios as a prognostic factor in patients who underwent surgery for ovarian mass.</p><p><strong>Material and methods: </strong>We retrospectively studied the patients admitted in the Department of Gynaecology due to adnexal mass. The potential association of the neutrophil-to-lymphocyte-ratio (NLR), neutrophil-to-monocyte (NMR), platelet-to-lymphocyte (PLR), lymphocyte-to-monocyte (LMR), monocyte-to-platelet, and malignancy was evaluated.</p><p><strong>Results: </strong>Patients with malignant tumours were found with significantly higher ratios of NLR (<i>p</i> < 0.001) and PLR (<i>p</i> < 0.001) and lower LMR ratio (<i>p</i> < 0.001) compared to those with benign tumours. Furthermore, higher lymphocyte count (<i>p</i> = 0.04) and platelet count (<i>p</i> = 0.004) were found in cancer patients when compared with borderline tumours. No significant variations were detected regarding white blood cell count (<i>p</i> = 0.238), NMR ratio (<i>p</i> = 0.28), platelet-to-neutrophil ratio (<i>p</i> = 0.12), and platelet-to-monocyte ratio (<i>p</i> = 0.34).</p><p><strong>Conclusions: </strong>Inflammation biomarker ratios can easily and inexpensive assist in distinguishing malignant ovarian tumours from benign ones.</p>\",\"PeriodicalId\":49354,\"journal\":{\"name\":\"Wspolczesna Onkologia-Contemporary Oncology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.9000,\"publicationDate\":\"2021-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f9/9f/WO-25-43726.PMC8063895.pdf\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Wspolczesna Onkologia-Contemporary Oncology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5114/wo.2021.105072\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2021/4/15 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"ONCOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Wspolczesna Onkologia-Contemporary Oncology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5114/wo.2021.105072","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2021/4/15 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"ONCOLOGY","Score":null,"Total":0}
The role of inflammation biomarkers in differential diagnosis of pelvic tumours of ovarian origin: a single-centre observational study.
Aim of the study: Our aim was to analyse the feasibility of white blood cell and platelet counts along with their ratios as a prognostic factor in patients who underwent surgery for ovarian mass.
Material and methods: We retrospectively studied the patients admitted in the Department of Gynaecology due to adnexal mass. The potential association of the neutrophil-to-lymphocyte-ratio (NLR), neutrophil-to-monocyte (NMR), platelet-to-lymphocyte (PLR), lymphocyte-to-monocyte (LMR), monocyte-to-platelet, and malignancy was evaluated.
Results: Patients with malignant tumours were found with significantly higher ratios of NLR (p < 0.001) and PLR (p < 0.001) and lower LMR ratio (p < 0.001) compared to those with benign tumours. Furthermore, higher lymphocyte count (p = 0.04) and platelet count (p = 0.004) were found in cancer patients when compared with borderline tumours. No significant variations were detected regarding white blood cell count (p = 0.238), NMR ratio (p = 0.28), platelet-to-neutrophil ratio (p = 0.12), and platelet-to-monocyte ratio (p = 0.34).
Conclusions: Inflammation biomarker ratios can easily and inexpensive assist in distinguishing malignant ovarian tumours from benign ones.
期刊介绍：
Contemporary Oncology is a journal aimed at oncologists, oncological surgeons, hematologists, radiologists, pathologists, radiotherapists, palliative care specialists, psychologists, nutritionists, and representatives of any other professions, whose interests are related to cancer. Manuscripts devoted to basic research in the field of oncology are also welcomed.
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