冠状动脉慢血流现象与颈动脉股脉波速度及主动脉弹性特性的关系。

IF 1.5 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
JRSM Cardiovascular Disease Pub Date : 2020-11-11 eCollection Date: 2020-01-01 DOI:10.1177/2048004020973094
Hasan Akkaya, Ertuğrul Emre Güntürk
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引用次数: 0

摘要

在本研究中,我们旨在探讨冠状动脉慢血流(CSF)与颈-股脉波速度(CFPWV)的关系。方法:78例脑脊液患者(女性27例,平均年龄43.95±7.28岁)和70例健康人(女性22例,平均年龄44.34±7.08岁)纳入研究。通过CFPWV对两组进行动脉硬度测量,这被认为是金标准。评估两组患者的主动脉弹性特性(ASI-β和主动脉扩张性)。结果:与对照组相比,CSF组CFPWV和主动脉扩张系数显著升高,ASI-β值显著降低。所有冠状动脉TIMI框架计数(TFC)与CFPWV和主动脉扩张率呈正相关,TFC与ASI-β呈负相关。结果表明,CFPWV预测CSF的特异性为97%,敏感性为98%,临界值为7.68 (ROC area = 994), p结论:脑脊液患者动脉僵硬度增加,提示脑脊液是一种全身性病理而非局部疾病,动脉粥样硬化等全身性病因在病因学中起作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

The relationship between coronary slow flow phenomenon and carotid femoral pulse wave velocity and aortic elastic properties.

The relationship between coronary slow flow phenomenon and carotid femoral pulse wave velocity and aortic elastic properties.

The relationship between coronary slow flow phenomenon and carotid femoral pulse wave velocity and aortic elastic properties.

The relationship between coronary slow flow phenomenon and carotid femoral pulse wave velocity and aortic elastic properties.

Introduction: In this study, we aimed to investigate the relationship between coronary slow flow (CSF) and carotid-femoral pulse wave velocity (CFPWV).

Methods: 78 (27 women, mean age 43.95 ± 7.28) patients with CSF, and 70 (22 women, mean age 44.34 ± 7.08) healthy individuals were included in the study. Arterial stiffness measurement was performed to both groups via CFPWV, which is considered the gold standard. Aortic elastic properties (ASI-β and aortic distensibility) were evaluated in both groups.

Results: The CSF group had significantly higher CFPWV and aortic distensibility values and significantly lower ASI-β values compared to the control group. There was a positive correlation between TIMI frame count (TFC) obtained in all coronary arteries and CFPWV and aortic distensibility, and a negative correlation between TFC and ASI-β. It was determined that CFPWV predicted CSF with 97% specificity and 98% sensitivity at a 7.68 cut-off value (ROC area = 994, p < 0.001). ASI-β was determined to predict CSF with 64% specificity and 47% sensitivity at a 2.98 cut-off value (ROC area = 047, p < 0.001). Aortic distensibility was determined to predict CSF with 76% specificity and 79% sensitivity at a 3.94 cut-off value (ROC area = 706, p < 0.001).

Conclusion: Arterial stiffness increases in CSF patients, suggesting that CSF is a systemic pathology rather than a local disease and that a systemic cause such as atherosclerosis plays a role in etiology.

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来源期刊
JRSM Cardiovascular Disease
JRSM Cardiovascular Disease CARDIAC & CARDIOVASCULAR SYSTEMS-
自引率
6.20%
发文量
12
审稿时长
12 weeks
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