布鲁顿酪氨酸激酶抑制剂治疗患者的侵袭性真菌感染。

4区医学 Q3 Medicine

Netherlands Journal of Medicine Pub Date : 2020-09-01

A Dunbar, M E Joosse, F de Boer, M Eefting, B J A Rijnders

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引用次数: 0

摘要

布鲁顿酪氨酸激酶(BTK)抑制剂越来越多地用于未经治疗和以前治疗过的慢性淋巴细胞白血病(CLL)患者。侵袭性真菌感染(IFI)在前btk时代治疗的CLL患者中很少观察到。在这篇文章中，我们描述了两名在使用BTK抑制剂伊鲁替尼治疗期间发生IFI的CLL患者。本文描述了这种并发症的非典型表现和严重的病程。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

本刊更多论文

Invasive fungal infections in patients treated with Bruton's tyrosine kinase inhibitors.

Bruton's tyrosine kinase (BTK) inhibitors are increasingly used in untreated and previously treated chronic lymphocytic leukaemia (CLL) patients. Invasive fungal infections (IFI) were rarely observed in patients treated for CLL in the pre-BTK era. In this article, we describe two patients with CLL who developed an IFI during treatment with the BTK inhibitor ibrutinib. The atypical presentation and the serious course of this complication are described.

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来源期刊

Netherlands Journal of Medicine 医学-医学：内科

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： The Netherlands Journal of Medicine publishes papers in all relevant fields of internal medicine. In addition to reports of original clinical and experimental studies, reviews on topics of interest or importance, case reports, book reviews and letters to the editor are welcomed.