Nikola Todorovic, Dejan Javorac, Valdemar Stajer, Sergej M Ostojic
{"title":"过饱和富氢水浴对年轻男性进行高强度偏心运动后肌肉损伤和酸痛感知生物标志物的影响。","authors":"Nikola Todorovic, Dejan Javorac, Valdemar Stajer, Sergej M Ostojic","doi":"10.1155/2020/8836070","DOIUrl":null,"url":null,"abstract":"<p><p>High-intensity eccentric exercise can cause a delayed onset of muscle soreness (DOMS), a short-term condition characterized by muscle damage and tenderness that might hold up recovery and jeopardize exercise routine. Previous studies indicated that hydrogen-rich water (HRW) might be a helpful topical intervention to boost recovery in musculoskeletal medicine, yet no data are available concerning the effectiveness and safety of whole-body bathing with supersaturated HRW after DOMS-inducing exercise. This study evaluates the effects of a single-session bathing with HRW on biochemical markers of muscular damage in healthy young men. The six volunteers who were exposed to DOMS-inducing eccentric exercise were assigned to either supersaturated HRW or control whole-body bathing in a double-blind crossover design. Immediately after an exercise session, the participants were immersed up to the neck into a 200 L bathtub with supersaturated HRW (8 mg of H<sub>2</sub> per L) or control water (no hydrogen) for 30 min. Blood biomarkers of inflammation and muscular damage and Visual Analogue Scale (VAS) scores for muscle soreness were assessed at baseline (before exercise) and at 24-hour follow-up. Two-way ANOVA revealed a significant difference between two groups in serum creatine kinase (CK) response over the period of intervention (<i>P</i>=0.04). A single-session bathing in HRW prevented a rise in circulating biomarkers of muscular damage induced by exercise at 24-hour follow-up, retaining the levels of all biomarkers similar to the baseline values (<i>P</i> > 0.05). On the other hand, serum CK, aldolase, and aspartate transaminase were significantly elevated at 24-hour follow-up as compared to the baseline levels after the control bath (342 ± 309 U/L vs. 465 ± 295 U/L; <i>P</i> > 0.05). HRW bath also induced a significant drop in VAS scores for muscle soreness in comparison with control water, both immediately after an intervention (32.7 ± 8.6% vs. 20.0 ± 12.8%; <i>P</i>=0.02) and at 24-hour follow-up (31.6 ± 24.3% vs. 22.4 ± 27.5%; <i>P</i>=0.03), respectively. No participants reported any major side effects during the trial. This pilot study suggests that the whole-body bathing in supersaturated HRW is a safe procedure that attenuates muscular damage and can ease sore muscles after high-intensity eccentric exercise.</p>","PeriodicalId":73953,"journal":{"name":"","volume":"2020 ","pages":"8836070"},"PeriodicalIF":0.0,"publicationDate":"2020-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2020/8836070","citationCount":"5","resultStr":"{\"title\":\"The Effects of Supersaturated Hydrogen-Rich Water Bathing on Biomarkers of Muscular Damage and Soreness Perception in Young Men Subjected to High-Intensity Eccentric Exercise.\",\"authors\":\"Nikola Todorovic, Dejan Javorac, Valdemar Stajer, Sergej M Ostojic\",\"doi\":\"10.1155/2020/8836070\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>High-intensity eccentric exercise can cause a delayed onset of muscle soreness (DOMS), a short-term condition characterized by muscle damage and tenderness that might hold up recovery and jeopardize exercise routine. Previous studies indicated that hydrogen-rich water (HRW) might be a helpful topical intervention to boost recovery in musculoskeletal medicine, yet no data are available concerning the effectiveness and safety of whole-body bathing with supersaturated HRW after DOMS-inducing exercise. This study evaluates the effects of a single-session bathing with HRW on biochemical markers of muscular damage in healthy young men. The six volunteers who were exposed to DOMS-inducing eccentric exercise were assigned to either supersaturated HRW or control whole-body bathing in a double-blind crossover design. Immediately after an exercise session, the participants were immersed up to the neck into a 200 L bathtub with supersaturated HRW (8 mg of H<sub>2</sub> per L) or control water (no hydrogen) for 30 min. Blood biomarkers of inflammation and muscular damage and Visual Analogue Scale (VAS) scores for muscle soreness were assessed at baseline (before exercise) and at 24-hour follow-up. Two-way ANOVA revealed a significant difference between two groups in serum creatine kinase (CK) response over the period of intervention (<i>P</i>=0.04). A single-session bathing in HRW prevented a rise in circulating biomarkers of muscular damage induced by exercise at 24-hour follow-up, retaining the levels of all biomarkers similar to the baseline values (<i>P</i> > 0.05). On the other hand, serum CK, aldolase, and aspartate transaminase were significantly elevated at 24-hour follow-up as compared to the baseline levels after the control bath (342 ± 309 U/L vs. 465 ± 295 U/L; <i>P</i> > 0.05). HRW bath also induced a significant drop in VAS scores for muscle soreness in comparison with control water, both immediately after an intervention (32.7 ± 8.6% vs. 20.0 ± 12.8%; <i>P</i>=0.02) and at 24-hour follow-up (31.6 ± 24.3% vs. 22.4 ± 27.5%; <i>P</i>=0.03), respectively. No participants reported any major side effects during the trial. 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引用次数: 5
摘要
高强度的离心运动可能会导致延迟性肌肉酸痛(DOMS),这是一种以肌肉损伤和压痛为特征的短期状态,可能会阻碍恢复并危及日常锻炼。先前的研究表明,富氢水(HRW)可能是一种有助于促进肌肉骨骼医学恢复的局部干预措施,但没有数据表明,在doms诱导运动后,用过饱和HRW全身沐浴的有效性和安全性。本研究评估了HRW单次沐浴对健康年轻男性肌肉损伤生化指标的影响。在双盲交叉设计中,6名暴露于引起doms的偏心运动的志愿者被分配到过饱和HRW或控制全身沐浴。运动结束后,参与者立即被浸入200升HRW(每升8毫克H2)或对照水(无氢)的浴缸中30分钟。在基线(运动前)和24小时随访时评估炎症和肌肉损伤的血液生物标志物和视觉模拟量表(VAS)肌肉酸痛评分。双因素方差分析显示,两组在干预期间血清肌酸激酶(CK)反应有显著差异(P=0.04)。在24小时随访中,HRW中单次沐浴阻止了运动引起的肌肉损伤循环生物标志物的升高,所有生物标志物的水平保持与基线值相似(P > 0.05)。另一方面,24小时随访时,血清CK、醛缩酶和天冬氨酸转氨酶与对照液后的基线水平相比显著升高(342±309 U/L vs 465±295 U/L;P > 0.05)。与对照组水相比,HRW浴在干预后立即引起肌肉酸痛VAS评分显著下降(32.7±8.6% vs 20.0±12.8%;P = 0.02), 24小时跟踪(31.6±24.3%和22.4±27.5%;分别P = 0.03)。在试验期间,没有参与者报告有任何主要的副作用。这项初步研究表明,全身沐浴在过饱和HRW中是一种安全的方法,可以减轻肌肉损伤,缓解高强度离心运动后的肌肉酸痛。
The Effects of Supersaturated Hydrogen-Rich Water Bathing on Biomarkers of Muscular Damage and Soreness Perception in Young Men Subjected to High-Intensity Eccentric Exercise.
High-intensity eccentric exercise can cause a delayed onset of muscle soreness (DOMS), a short-term condition characterized by muscle damage and tenderness that might hold up recovery and jeopardize exercise routine. Previous studies indicated that hydrogen-rich water (HRW) might be a helpful topical intervention to boost recovery in musculoskeletal medicine, yet no data are available concerning the effectiveness and safety of whole-body bathing with supersaturated HRW after DOMS-inducing exercise. This study evaluates the effects of a single-session bathing with HRW on biochemical markers of muscular damage in healthy young men. The six volunteers who were exposed to DOMS-inducing eccentric exercise were assigned to either supersaturated HRW or control whole-body bathing in a double-blind crossover design. Immediately after an exercise session, the participants were immersed up to the neck into a 200 L bathtub with supersaturated HRW (8 mg of H2 per L) or control water (no hydrogen) for 30 min. Blood biomarkers of inflammation and muscular damage and Visual Analogue Scale (VAS) scores for muscle soreness were assessed at baseline (before exercise) and at 24-hour follow-up. Two-way ANOVA revealed a significant difference between two groups in serum creatine kinase (CK) response over the period of intervention (P=0.04). A single-session bathing in HRW prevented a rise in circulating biomarkers of muscular damage induced by exercise at 24-hour follow-up, retaining the levels of all biomarkers similar to the baseline values (P > 0.05). On the other hand, serum CK, aldolase, and aspartate transaminase were significantly elevated at 24-hour follow-up as compared to the baseline levels after the control bath (342 ± 309 U/L vs. 465 ± 295 U/L; P > 0.05). HRW bath also induced a significant drop in VAS scores for muscle soreness in comparison with control water, both immediately after an intervention (32.7 ± 8.6% vs. 20.0 ± 12.8%; P=0.02) and at 24-hour follow-up (31.6 ± 24.3% vs. 22.4 ± 27.5%; P=0.03), respectively. No participants reported any major side effects during the trial. This pilot study suggests that the whole-body bathing in supersaturated HRW is a safe procedure that attenuates muscular damage and can ease sore muscles after high-intensity eccentric exercise.