{"title":"ROS1阳性非小细胞肺癌合并肺栓塞1例22岁女性。","authors":"Ananda Datta, Satya Padmaja Mantha, Suvradeep Mitra, Prasanta Mohapatra, M Srikanth Goud, Manoj Kumar Panigrahi","doi":"10.4081/monaldi.2020.1435","DOIUrl":null,"url":null,"abstract":"<p><p>ROS1-rearrangement occurs in 1-2% of non-small cell lung cancer (NSCLC). This mutation is predominantly seen in relatively young, non-smoker, female with adenocarcinoma. Association of pulmonary embolism with ROS1-rearranged NSCLC has been suggested. We report a case of a 22-year-old woman with ROS1-positive NSCLC and pulmonary embolism. This case possibly represents the youngest patient in the literature.</p>","PeriodicalId":520711,"journal":{"name":"Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace","volume":" ","pages":""},"PeriodicalIF":0.8000,"publicationDate":"2020-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4081/monaldi.2020.1435","citationCount":"4","resultStr":"{\"title\":\"ROS1 positive non-small cell lung cancer with pulmonary embolism in a 22-year woman.\",\"authors\":\"Ananda Datta, Satya Padmaja Mantha, Suvradeep Mitra, Prasanta Mohapatra, M Srikanth Goud, Manoj Kumar Panigrahi\",\"doi\":\"10.4081/monaldi.2020.1435\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>ROS1-rearrangement occurs in 1-2% of non-small cell lung cancer (NSCLC). This mutation is predominantly seen in relatively young, non-smoker, female with adenocarcinoma. Association of pulmonary embolism with ROS1-rearranged NSCLC has been suggested. We report a case of a 22-year-old woman with ROS1-positive NSCLC and pulmonary embolism. This case possibly represents the youngest patient in the literature.</p>\",\"PeriodicalId\":520711,\"journal\":{\"name\":\"Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2020-08-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.4081/monaldi.2020.1435\",\"citationCount\":\"4\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4081/monaldi.2020.1435\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4081/monaldi.2020.1435","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
ROS1 positive non-small cell lung cancer with pulmonary embolism in a 22-year woman.
ROS1-rearrangement occurs in 1-2% of non-small cell lung cancer (NSCLC). This mutation is predominantly seen in relatively young, non-smoker, female with adenocarcinoma. Association of pulmonary embolism with ROS1-rearranged NSCLC has been suggested. We report a case of a 22-year-old woman with ROS1-positive NSCLC and pulmonary embolism. This case possibly represents the youngest patient in the literature.
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