严重急性呼吸综合征冠状病毒-2和肺结核:融合可能是致命的。

Abhijeet Singh, Rajendra Prasad, Ayush Gupta, Kamanasish Das, Nikhil Gupta
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引用次数: 20

摘要

与SARS-CoV-2相关的疾病,也被称为2019冠状病毒病或COVID-19,已在短时间内蔓延到全球200多个国家,成为对公共卫生的潜在威胁。结核病已经作为一种前所未有的流行病在世界范围内存在了好几年。这两种疾病有许多重叠的特征,但也有显著的差异。与COVID-19的急性或快速进展相比,结核病的症状通常是慢性的。关于结核病和COVID-19合并感染的证据很少。预计活动性、既往治疗过或潜伏型结核病患者感染COVID-19的不良后果风险更大。目前,这两种疾病之间的关系尚不清楚,需要更多的研究来分析受这两种疾病影响的患者的相互作用和结果决定因素。世界上大多数国家都在全国范围内实施了封锁措施,以促进社会距离,这是缓解新冠肺炎大流行蔓延的一项重要预防措施。然而,确保规划服务的顺利运作变得相当具有挑战性,导致常规结核病治疗中断,导致感染传播。卫生当局应制定政策,在当前COVID-19大流行时期不间断地提供诊断、管理和预防服务,为结核病患者提供支持。应努力同时控制这两种疾病,避免在不久的将来出现不良后果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Severe acute respiratory syndrome coronavirus-2 and pulmonary tuberculosis: convergence can be fatal.

Disease associated with SARS-CoV-2 also termed as Coronavirus disease 2019 or COVID-19, has become a potential threat to public health by spreading across more than 200 countries worldwide within a short span of time. Tuberculosis (TB) is already existing as unprecedented pandemic worldwide over several years. Both diseases have many overlapping features but there are striking differences too. There is usually chronicity of symptoms in TB as compared to acute or rapid progression in COVID-19. Little evidence exists regarding TB and COVID-19 coinfection. It is anticipated that person with TB either in active, previously treated or latent forms are more at risk of poor outcomes with COVID-19. The relationship between the two diseases is still unclear at present, and more studies are needed to enable analyses of interactions and determinants of outcomes in patients affected by both the diseases. Most of the countries across the world imposed nationwide lockdown to promote social distancing, which is one important preventive measure to mitigate the spread of COVID-19 pandemic. However, it becomes quite challenging to ensure smooth functioning of programmatic services, leading to disruption of routine TB care, leading to transmission of infection. Health authorities should frame polices that can support TB patients by providing diagnostic, management and prevention services without any interruption during this era of ongoing COVID-19 pandemic. Effort should be made to control both the diseases simultaneously and avoid unfavourable outcome in near future.

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