儿童动脉缺血性卒中:临床表现、危险因素和儿童NIH卒中量表在一系列智利患者。

Cell medicine Pub Date : 2018-05-29 eCollection Date: 2018-01-01 DOI:10.1177/2155179018760330
María José Hidalgo, Daniela Muñoz, Fernanda Balut, Mónica Troncoso, Susana Lara, Andrés Barrios, Patricia Parra
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引用次数: 2

摘要

脑卒中是儿童发病和死亡的重要原因。临床表现多样,多种危险因素已被描述。本回顾性研究的目的是描述一系列被诊断为动脉缺血性卒中(AIS)的智利儿童患者的临床表现、危险因素和儿童国立卫生研究院卒中量表(PedNIHSS)。被诊断为AIS的儿童年龄在29天至18岁之间(1989年至2016年)。描述了临床特征和危险因素。对年龄大于4个月的患者进行PedNIHSS严重程度评分。纳入62例患者,66%为男性,平均发病年龄为3.5岁。79%表现为运动障碍,45%表现为癫痫发作,15%表现为意识障碍。82%的患者单侧中风,73%的患者前循环受到影响。主要危险因素为动脉病变(63%)和感染(43%)。PedNIHSS的平均值为7.6,范围在0到17之间。在可以应用χ2检验的类别中,只有急性全身疾病类别具有统计学意义(P = 0.03),在年龄小于3岁的患者组中更高。我们证实男性在AIS中占优势,最常见的症状是运动障碍。我们发现在所有患者中至少有1个危险因素具有完整的信息。我们证实动脉病变是最常见的危险因素,3岁以下患者急性全身性疾病发生率更高,差异有统计学意义(P = 0.03)。在PedNIHSS评分中,大多数患者表现为轻度至中度严重程度。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Pediatric Arterial Ischemic Stroke: Clinical Presentation, Risk Factors, and Pediatric NIH Stroke Scale in a Series of Chilean Patients.

Pediatric Arterial Ischemic Stroke: Clinical Presentation, Risk Factors, and Pediatric NIH Stroke Scale in a Series of Chilean Patients.

Pediatric Arterial Ischemic Stroke: Clinical Presentation, Risk Factors, and Pediatric NIH Stroke Scale in a Series of Chilean Patients.

Pediatric Arterial Ischemic Stroke: Clinical Presentation, Risk Factors, and Pediatric NIH Stroke Scale in a Series of Chilean Patients.

Stroke is an important cause of morbidity and mortality in children. Clinical presentation is diverse, and multiple risk factors have been described. The aim of this retrospective study is to describe the clinical presentation, risk factors, and the Pediatric National Institute of Health Stroke Scale (PedNIHSS) in a series of pediatric Chilean patients with the diagnosis of arterial ischemic stroke (AIS). Children diagnosed with AIS aged between 29 d and 18 y were enrolled (1989 to 2016). Clinical characteristics and risk factors were described. PedNIHSS severity score was estimated for patients older than 4 mo of age. Sixty-two patients were included, 66% were male, and the mean age of presentation was 3.5 y. Seventy-nine percent presented motor deficit, 45% seizures, and 15% consciousness impairment. Eighty-two percent had a unilateral stroke and 73% had anterior circulation territory affected. The main risk factors were arteriopathy (63%) and infection (43%). The PedNIHSS mean was 7.6, ranging between 0 and 17. In the categories in which it was possible to apply χ2 test, only the acute systemic conditions category was statistically significant (P = 0.03), being higher in the group of patients younger than 3 y old. We confirmed male predominance in AIS and the most frequent presenting symptom was motor deficit. We found at least 1 risk factor in all patients with complete information. We confirmed arteriopathy as the most frequent risk factor, and acute systemic conditions were higher in patients younger than 3 y old with statistical significance (P = 0.03). The majority of patients presented mild to moderate severity in the PedNIHSS score.

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来源期刊
Cell medicine
Cell medicine MEDICINE, RESEARCH & EXPERIMENTAL-
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