减少感染者接触时间活动对SIR模型中直接传播呼吸道感染的动态和控制的影响

IF 4.1 3区 数学 Q1 Mathematics
Advances in Difference Equations Pub Date : 2020-01-01 Epub Date: 2020-05-27 DOI:10.1186/s13662-020-02708-8
Muntaser Safan
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引用次数: 1

摘要

本文旨在研究使用教育策略对减少控制SIR模型所代表的呼吸道传播感染所需努力的影响,同时考虑到感染者和非感染者之间接触的异质性。因此,一个新的发病率函数,其中感染和非感染个体之间的接触时间活动的差异被考虑在内,被制定。对模型进行了平衡分析和稳定性分析。将该模型扩展到包括群体免疫的影响,分析表明,感染个体接触活动时间减少百分比P - r越高,消除感染所需的临界疫苗接种覆盖水平P - r越低,因此,感染的最小消除努力越低。考虑了对基本模型的另一个扩展,以包括基于以最大容量治疗I以速率α治疗受感染个体的控制策略。平衡分析表明存在多个亚临界和超临界地方性平衡,稳定性分析表明模型存在Hopf分岔。模拟结果表明,最大处理能力I越高,感染个体时间活动P r -的临界减少值越低,产生Hopf分岔。采用与甲型流感病例相对应的参数值进行了模拟。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Impact of reduction in contact time activity of infected individuals on the dynamics and control of directly transmitted respiratory infections in SIR models.

Impact of reduction in contact time activity of infected individuals on the dynamics and control of directly transmitted respiratory infections in SIR models.

Impact of reduction in contact time activity of infected individuals on the dynamics and control of directly transmitted respiratory infections in SIR models.

Impact of reduction in contact time activity of infected individuals on the dynamics and control of directly transmitted respiratory infections in SIR models.

This paper aims to study the impact of using an educational strategy on reducing the efforts needed to control respiratory transmitted infections represented by SIR models, taking into account heterogeneity in contacts between infected and non-infected individuals. Therefore, a new incidence function, in which the difference in contact time activity between infected and non-infected individuals is taken into account, is formulated. Equilibrium and stability analyses of the model have been carried out. The model has been extended to include the effect of herd immunity and the analysis showed that the higher the percent reduction P ˆ r in the contact-activity time of infected individuals is, the lower the critical vaccination coverage level p c required to eliminate the infection is, and therefore, the lower the infection's minimum elimination effort is. Another extension of the basic model to include a control strategy based on treating infected individuals at rate α with a maximum capacity treatment I has been considered. The equilibrium analysis showed the existence of multiple subcritical and supercritical endemic equilibria, while the stability analysis showed that the model exhibits a Hopf bifurcation. Simulations showed that the higher the maximum treatment capacity I is, the lower the value of the critical reduction in infected individuals' time activity P r , at which a Hopf bifurcation is generated, is. Simulations with parameter values corresponding to the case of influenza A have been carried out.

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来源期刊
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审稿时长
4-8 weeks
期刊介绍: The theory of difference equations, the methods used, and their wide applications have advanced beyond their adolescent stage to occupy a central position in applicable analysis. In fact, in the last 15 years, the proliferation of the subject has been witnessed by hundreds of research articles, several monographs, many international conferences, and numerous special sessions. The theory of differential and difference equations forms two extreme representations of real world problems. For example, a simple population model when represented as a differential equation shows the good behavior of solutions whereas the corresponding discrete analogue shows the chaotic behavior. The actual behavior of the population is somewhere in between. The aim of Advances in Difference Equations is to report mainly the new developments in the field of difference equations, and their applications in all fields. We will also consider research articles emphasizing the qualitative behavior of solutions of ordinary, partial, delay, fractional, abstract, stochastic, fuzzy, and set-valued differential equations. Advances in Difference Equations will accept high-quality articles containing original research results and survey articles of exceptional merit.
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