{"title":"COVID-19患者眼表中的SARS-CoV-2","authors":"Hua-Tao Xie, Shi-Yun Jiang, Kang-Kang Xu, Xin Liu, Bing Xu, Lin Wang, Ming-Chang Zhang","doi":"10.1186/s40662-020-00189-0","DOIUrl":null,"url":null,"abstract":"<p><p>The 2019 novel coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread globally, while the routes of transmission of this virus are still controversial. We enrolled 33 patients, without any ocular manifestation, with their ocular surface swabs collected for virus detection. RNA was detected strong positive in samples of both eyes from two patients. Therefore, SARS-CoV-2 may exist in the normal ocular surface of COVID-19 patients, suggesting that this virus might be spread through conjunctival contact.</p>","PeriodicalId":520624,"journal":{"name":"Eye and vision (London, England)","volume":" ","pages":"23"},"PeriodicalIF":0.0000,"publicationDate":"2020-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s40662-020-00189-0","citationCount":"90","resultStr":"{\"title\":\"SARS-CoV-2 in the ocular surface of COVID-19 patients.\",\"authors\":\"Hua-Tao Xie, Shi-Yun Jiang, Kang-Kang Xu, Xin Liu, Bing Xu, Lin Wang, Ming-Chang Zhang\",\"doi\":\"10.1186/s40662-020-00189-0\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The 2019 novel coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread globally, while the routes of transmission of this virus are still controversial. We enrolled 33 patients, without any ocular manifestation, with their ocular surface swabs collected for virus detection. RNA was detected strong positive in samples of both eyes from two patients. Therefore, SARS-CoV-2 may exist in the normal ocular surface of COVID-19 patients, suggesting that this virus might be spread through conjunctival contact.</p>\",\"PeriodicalId\":520624,\"journal\":{\"name\":\"Eye and vision (London, England)\",\"volume\":\" \",\"pages\":\"23\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-04-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1186/s40662-020-00189-0\",\"citationCount\":\"90\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Eye and vision (London, England)\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1186/s40662-020-00189-0\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2020/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Eye and vision (London, England)","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1186/s40662-020-00189-0","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2020/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
SARS-CoV-2 in the ocular surface of COVID-19 patients.
The 2019 novel coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread globally, while the routes of transmission of this virus are still controversial. We enrolled 33 patients, without any ocular manifestation, with their ocular surface swabs collected for virus detection. RNA was detected strong positive in samples of both eyes from two patients. Therefore, SARS-CoV-2 may exist in the normal ocular surface of COVID-19 patients, suggesting that this virus might be spread through conjunctival contact.