Erick A Perez-Alday, Christopher Hamilton, Annabel Li-Pershing, Jose M Monroy-Trujillo, Michelle Estrella, Stephen M Sozio, Bernard Jaar, Rulan Parekh, Larisa Tereshchenko
{"title":"心电图测量全局电异质性的可重复性。","authors":"Erick A Perez-Alday, Christopher Hamilton, Annabel Li-Pershing, Jose M Monroy-Trujillo, Michelle Estrella, Stephen M Sozio, Bernard Jaar, Rulan Parekh, Larisa Tereshchenko","doi":"10.22489/cinc.2018.162","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Global electrical heterogeneity (GEH) is a useful predictor of adverse clinical outcomes. However, reproducibility of GEH measurements on 10-second routine clinical ECG is unknown.</p><p><strong>Methods: </strong>Data of the prospective cohort study of incident hemodialysis patients (n=253; mean age 54.6±13.5y; 56% male; 79% African American) were analysed. Two random 10-second segments of 5-minute ECG recording in sinus rhythm were compared. GEH was measured as spatial QRS-T angle, spatial ventricular gradient (SVG) magnitude and direction (azimuth and elevation), and a scalar value of SVG measured by (1) sum absolute QRST integral (SAI QRST), and (2) QT integral on vector magnitude signal (iVM<sub>QT</sub>). Bland-Altman analysis was used to calculate agreement.</p><p><strong>Results: </strong>For all studied vectorcardiographic metrics, agreement was substantial (Lin's concordance coefficient >0.98), and precision was perfect (>99.99%). 95% limits of agreement were ±14° for spatial QRS-T angle, ±13° for SVG azimuth, ±4° for SVG elevation, ±14 mV*ms for SVG magnitude, and ±17 mV*ms for SAI QRST. SAI QRST and iVM<sub>QT</sub> were in substantial agreement with each other.</p><p><strong>Conclusion: </strong>Reproducibility of a 10-second automated GEH ECG measurements was substantial, and precision was perfect.</p>","PeriodicalId":72683,"journal":{"name":"Computing in cardiology","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2018-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158900/pdf/nihms-1032512.pdf","citationCount":"3","resultStr":"{\"title\":\"The Reproducibility of Global Electrical Heterogeneity ECG Measurements.\",\"authors\":\"Erick A Perez-Alday, Christopher Hamilton, Annabel Li-Pershing, Jose M Monroy-Trujillo, Michelle Estrella, Stephen M Sozio, Bernard Jaar, Rulan Parekh, Larisa Tereshchenko\",\"doi\":\"10.22489/cinc.2018.162\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Global electrical heterogeneity (GEH) is a useful predictor of adverse clinical outcomes. However, reproducibility of GEH measurements on 10-second routine clinical ECG is unknown.</p><p><strong>Methods: </strong>Data of the prospective cohort study of incident hemodialysis patients (n=253; mean age 54.6±13.5y; 56% male; 79% African American) were analysed. Two random 10-second segments of 5-minute ECG recording in sinus rhythm were compared. GEH was measured as spatial QRS-T angle, spatial ventricular gradient (SVG) magnitude and direction (azimuth and elevation), and a scalar value of SVG measured by (1) sum absolute QRST integral (SAI QRST), and (2) QT integral on vector magnitude signal (iVM<sub>QT</sub>). Bland-Altman analysis was used to calculate agreement.</p><p><strong>Results: </strong>For all studied vectorcardiographic metrics, agreement was substantial (Lin's concordance coefficient >0.98), and precision was perfect (>99.99%). 95% limits of agreement were ±14° for spatial QRS-T angle, ±13° for SVG azimuth, ±4° for SVG elevation, ±14 mV*ms for SVG magnitude, and ±17 mV*ms for SAI QRST. SAI QRST and iVM<sub>QT</sub> were in substantial agreement with each other.</p><p><strong>Conclusion: </strong>Reproducibility of a 10-second automated GEH ECG measurements was substantial, and precision was perfect.</p>\",\"PeriodicalId\":72683,\"journal\":{\"name\":\"Computing in cardiology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158900/pdf/nihms-1032512.pdf\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Computing in cardiology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.22489/cinc.2018.162\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2019/6/24 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Computing in cardiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22489/cinc.2018.162","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2019/6/24 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
The Reproducibility of Global Electrical Heterogeneity ECG Measurements.
Background: Global electrical heterogeneity (GEH) is a useful predictor of adverse clinical outcomes. However, reproducibility of GEH measurements on 10-second routine clinical ECG is unknown.
Methods: Data of the prospective cohort study of incident hemodialysis patients (n=253; mean age 54.6±13.5y; 56% male; 79% African American) were analysed. Two random 10-second segments of 5-minute ECG recording in sinus rhythm were compared. GEH was measured as spatial QRS-T angle, spatial ventricular gradient (SVG) magnitude and direction (azimuth and elevation), and a scalar value of SVG measured by (1) sum absolute QRST integral (SAI QRST), and (2) QT integral on vector magnitude signal (iVMQT). Bland-Altman analysis was used to calculate agreement.
Results: For all studied vectorcardiographic metrics, agreement was substantial (Lin's concordance coefficient >0.98), and precision was perfect (>99.99%). 95% limits of agreement were ±14° for spatial QRS-T angle, ±13° for SVG azimuth, ±4° for SVG elevation, ±14 mV*ms for SVG magnitude, and ±17 mV*ms for SAI QRST. SAI QRST and iVMQT were in substantial agreement with each other.
Conclusion: Reproducibility of a 10-second automated GEH ECG measurements was substantial, and precision was perfect.
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