Madeline H Meier, Jordan Beardslee, Dustin Pardini
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Analyses also accounted for time-varying factors as potential confounds (other substance use, externalizing problems, subclinical psychotic symptoms). Results showed that increases in recent cannabis use and cumulative prior years of weekly cannabis use were each associated with increases in depression symptoms and anxiety/depression problems. After controlling for time-varying covariates, increases in cumulative prior years of weekly cannabis use, but not recent cannabis use, remained associated with increases in depression symptoms and anxiety/depression problems. Specifically, each additional year of prior weekly cannabis use was associated with a small increase in depression symptoms (b = 0.012, p = .005) and anxiety/depression problems (b = 0.009, p = .001). Associations did not vary systematically across time. There was also no evidence of reverse causation. 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引用次数: 9
摘要
这项研究测试了近期和累积大麻使用的增加是否与青春期到青年期内化问题的增加有关。参与者是来自社区样本的男孩,每年评估15-26岁(N = 506)。男孩每年报告他们的大麻使用情况、抑郁症状和焦虑/抑郁问题。暴露是指某一年中使用大麻的频率(不使用、<每周使用、每周或更频繁使用)和以前每周使用大麻的累积年份。结果是给定年份的抑郁症状和焦虑/抑郁问题。随着时间的推移,分析检查了暴露变化和结果之间的个人内部关联,从而消除了“固定”(不变)的个体差异作为潜在的混淆。分析还考虑了时变因素作为潜在的混杂因素(其他物质使用、外化问题、亚临床精神病症状)。结果表明,最近大麻使用量的增加和过去几年每周大麻使用量的累积都与抑郁症状和焦虑/抑郁问题的增加有关。在控制了时变协变量后,前几年每周大麻使用量的增加,而不是最近大麻使用量的增加,仍然与抑郁症状和焦虑/抑郁问题的增加有关。具体而言,之前每周使用大麻的时间每增加一年,抑郁症状(b = 0.012, p = 0.005)和焦虑/抑郁问题(b = 0.009, p = 0.001)都会小幅增加。这些关联并没有随时间系统性地变化。也没有反向因果关系的证据。当男孩每周吸食大麻的时间越长,他们的内化问题就会增加,这表明预防每周吸食大麻的重要性。
Associations between Recent and Cumulative Cannabis Use and Internalizing Problems in Boys from Adolescence to Young Adulthood.
This study tested whether increases in recent and cumulative cannabis use were each associated with increases in internalizing problems from adolescence to young adulthood. Participants were boys from a community sample that was assessed annually from ~age 15-26 (N = 506). Boys reported on their cannabis use, depression symptoms, and anxiety/depression problems each year. Exposures were frequency of cannabis use in a given year (no use, < weekly use, weekly or more frequent use) and cumulative prior years of weekly cannabis use. Outcomes were depression symptoms and anxiety/depression problems in a given year. Analyses examined within-person associations between changes in exposures and outcomes over time, which eliminated "fixed" (unchanging) individual differences as potential confounds. Analyses also accounted for time-varying factors as potential confounds (other substance use, externalizing problems, subclinical psychotic symptoms). Results showed that increases in recent cannabis use and cumulative prior years of weekly cannabis use were each associated with increases in depression symptoms and anxiety/depression problems. After controlling for time-varying covariates, increases in cumulative prior years of weekly cannabis use, but not recent cannabis use, remained associated with increases in depression symptoms and anxiety/depression problems. Specifically, each additional year of prior weekly cannabis use was associated with a small increase in depression symptoms (b = 0.012, p = .005) and anxiety/depression problems (b = 0.009, p = .001). Associations did not vary systematically across time. There was also no evidence of reverse causation. As boys engaged in weekly cannabis use for more years, they showed increases in internalizing problems, suggesting the importance of preventing chronic weekly cannabis use.
期刊介绍:
Research on Child and Adolescent Psychopathology brings together the latest innovative research that advances knowledge of psychopathology from infancy through adolescence. The journal publishes studies that have a strong theoretical framework and use a diversity of methods, with an emphasis on empirical studies of the major forms of psychopathology found in childhood disorders (e.g., disruptive behavior disorders, depression, anxiety, and autism spectrum disorder). Studies focus on the epidemiology, etiology, assessment, treatment, prognosis, and developmental course of these forms of psychopathology. Studies highlighting risk and protective factors; the ecology and correlates of children''s emotional, social, and behavior problems; and advances in prevention and treatment are featured.
Research on Child and Adolescent Psychopathology is the official journal of the International Society for Research in Child and Adolescent Psychopathology (ISRCAP), a multidisciplinary scientific society.